Pepcid ac and Nitrostat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pepcid ac (famotidine) and Nitrostat (nitroglycerin). Common drug interactions include aortic valve incompetence among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Pepcid ac and Nitrostat. It is created by eHealthMe based on reports of 68 people who take the same drugs from the FDA, and is updated regularly.

What is Pepcid ac?

Pepcid ac has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 9,573 Pepcid ac users. Check the latest studies of Pepcid ac.

What is Nitrostat?

Nitrostat has active ingredients of nitroglycerin. It is often used in chest pain. eHealthMe is studying from 14,082 Nitrostat users. Check the latest studies of Nitrostat.

On Jul, 24, 2026

68 people who take Pepcid ac and Nitrostat together, and have interactions are studied.

Pepcid ac and Nitrostat drug interactions.

What are the common drug interactions of Pepcid Ac and Nitrostat, by gender? *:

female:

Aortic valve incompetence
Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Ascites (accumulation of fluid in the abdominal cavity)
Asthenia (weakness)
Asthma
Atelectasis (partial or complete collapse of the lung)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Gastric disorder (disease of stomach)
Gastrointestinal motility disorder (abnormal intestinal contractions)
Infection
Pain in extremity
Peripheral swelling
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Vomiting
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

What are the common drug interactions of Pepcid Ac and Nitrostat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Renal failure (kidney dysfunction)
Nephrogenic anaemia (anaemia due to kidney disease)
Colorectal cancer metastatic (cancer of colon and rectal spreads to other parts)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Respiratory failure (inadequate gas exchange by the respiratory system)
Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)
Chronic kidney disease

40-49:

Chronic kidney disease
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic complication
Renal failure (kidney dysfunction)

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Nephrogenic anaemia (anaemia due to kidney disease)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
Renal injury (kidney injury)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Gait disturbance
Insomnia (sleeplessness)
Renal disorder (kidney disease)
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Abdominal pain

What are the existing conditions these people have? *

Pain: 21 people, 30.88%
High Blood Pressure: 19 people, 27.94%
High Blood Cholesterol: 14 people, 20.59%
Cardiac Disorder: 12 people, 17.65%
Diabetes: 9 people, 13.24%
Indigestion: 9 people, 13.24%
Blood Pressure Abnormal: 8 people, 11.76%
Infection: 7 people, 10.29%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 10.29%
Stable Angina (a constant chest pain): 7 people, 10.29%

* Approximation only. Some reports may have incomplete information.

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