Pepcid ac and Rabeprazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pepcid ac (famotidine) and Rabeprazole (rabeprazole sodium). Common drug interactions include irritability among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Pepcid ac and Rabeprazole. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Pepcid ac?

Pepcid ac has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 9,573 Pepcid ac users. Check the latest studies of Pepcid ac.

What is Rabeprazole?

Rabeprazole has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 31,689 Rabeprazole users. Check the latest studies of Rabeprazole.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 15, 2026

17 people who take Pepcid ac and Rabeprazole together, and have interactions are studied.

Pepcid ac and Rabeprazole drug interactions.

What are the common drug interactions of Pepcid Ac and Rabeprazole, by gender? *:

female:

Irritability
Libido decreased (loss of interest in sex)
Myalgia (muscle pain)
Neck pain
Oropharyngeal pain
Pain
Somnolence (a state of near-sleep, a strong desire for sleep)
Renal failure (kidney dysfunction)
Depression
Anxiety

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Death
Urinary tract infection

What are the common drug interactions of Pepcid Ac and Rabeprazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Depression
Disturbance in attention
Irritability
Libido decreased (loss of interest in sex)
Somnolence (a state of near-sleep, a strong desire for sleep)

30-39:

n/a

40-49:

Oropharyngeal pain
Pain
Myalgia (muscle pain)
Neck pain

50-59:

Renal failure (kidney dysfunction)
Anxiety
Depression
Chronic kidney disease
Urinary tract infection

60+:

Chronic kidney disease
Death
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

What are the existing conditions these people have? *

Pain: 11 people, 64.71%
Anaemia (lack of blood): 6 people, 35.29%
Diabetes: 6 people, 35.29%
Itching: 6 people, 35.29%
High Blood Pressure: 5 people, 29.41%
Depression: 4 people, 23.53%
Muscle Spasms (muscle contraction): 3 people, 17.65%
Indigestion: 2 people, 11.76%
Oedema (fluid collection in tissue): 2 people, 11.76%
Multiple Allergies (allergy to multiple agents): 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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