Pepcid ac and Viagra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pepcid ac (famotidine) and Viagra (sildenafil citrate). Common drug interactions include chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Pepcid ac and Viagra. It is created by eHealthMe based on reports of 86 people who take the same drugs from the FDA, and is updated regularly.

What is Pepcid ac?

Pepcid ac has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 9,573 Pepcid ac users. Check the latest studies of Pepcid ac.

What is Viagra?

Viagra has active ingredients of sildenafil citrate. It is often used in erection problems. eHealthMe is studying from 63,865 Viagra users. Check the latest studies of Viagra.



On Jul, 07, 2026

86 people who take Pepcid ac and Viagra together, and have interactions are studied.

Pepcid ac and Viagra drug interactions.

What are the common drug interactions of Pepcid Ac and Viagra, by gender? *:

female:

n/a

male:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Fall
  4. Loss of consciousness
  5. Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
  6. Pain
  7. Dizziness
  8. Erythema (redness of the skin)
  9. Headache (pain in head)
  10. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)

What are the common drug interactions of Pepcid Ac and Viagra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Renal injury (kidney injury)
  4. Depression
  5. Anxiety
  6. Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)
  7. Suicidal ideation
  8. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

40-49:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Renal cancer (cancer of kidney)
  4. Nephrogenic anaemia (anaemia due to kidney disease)
  5. Renal injury (kidney injury)
  6. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  7. Anaemia (lack of blood)
  8. Culture urine positive
  9. Dehydration (dryness resulting from the removal of water)
  10. Depression

50-59:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Renal impairment (severely reduced kidney function)
  4. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  5. Renal injury (kidney injury)
  6. Nephrogenic anaemia (anaemia due to kidney disease)
  7. Renal tubular necrosis (death of kidney tubules)
  8. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  9. Anxiety
  10. Depression

60+:

  1. Chronic kidney disease
  2. Dizziness
  3. Dyskinesia (abnormality or impairment of voluntary movement)
  4. Fatigue (feeling of tiredness)
  5. Oral discomfort (pain or irritation in mouth)
  6. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  7. Therapeutic response decreased (less preventive response)
  8. Back pain
  9. Balance disorder
  10. Blood pressure decreased

What are the existing conditions these people have? *

  1. High Blood Pressure: 34 people, 39.53%
  2. Pain: 25 people, 29.07%
  3. High Blood Cholesterol: 19 people, 22.09%
  4. Infection: 18 people, 20.93%
  5. Indigestion: 18 people, 20.93%
  6. Diabetes: 14 people, 16.28%
  7. Depression: 10 people, 11.63%
  8. Headache (pain in head): 9 people, 10.47%
  9. Inflammation: 9 people, 10.47%
  10. Fluid Retention (an abnormal accumulation of fluid in the blood): 9 people, 10.47%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Pepcid ac and Viagra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pepcid ac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Viagra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pepcid ac and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Viagra and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on famotidine and sildenafil citrate (the active ingredients of Pepcid ac and Viagra, respectively), and Pepcid ac and Viagra (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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