Pepcid and Fluoride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pepcid (famotidine) and Fluoride (fluoride). Common drug interactions include cough among females and amnesia among males.

The phase IV clinical study analyzes what interactions people have when they take Pepcid and Fluoride. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Pepcid?

Pepcid has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 55,774 Pepcid users. Check the latest studies of Pepcid.

What is Fluoride?

Fluoride has active ingredients of fluoride. eHealthMe is studying from 2,301 Fluoride users. Check the latest studies of Fluoride.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

44 people who take Pepcid and Fluoride together, and have interactions are studied.

What are the common drug interactions of Pepcid and Fluoride, by gender? *:

female:

Cough
Ear infection
Pain
Pneumonia
Sinusitis (inflammation of sinus)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Scoliosis (a medical condition in which a person's spine is curved from side to side)
Skin infection
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)

male:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Muscle spasms (muscle contraction)
Nephrogenic anaemia (anaemia due to kidney disease)
Rehabilitation therapy
Renal failure (kidney dysfunction)
Rib fracture
Sepsis (a severe blood infection that can lead to organ failure and death)
Small intestinal perforation (hole in small intestine)
Small intestine gangrene (small intestine tissue dies)

What are the common drug interactions of Pepcid and Fluoride, by age (0-1 to 60+)? *:

0-1:

Cough
Dyspnoea (difficult or laboured respiration)

2-9:

n/a

10-19:

Allergy to arthropod bite
Chronic kidney disease
Drug hypersensitivity
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Skin disorder (skin disease)

20-29:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cough
Ear infection
Pneumonia
Scoliosis (a medical condition in which a person's spine is curved from side to side)
Sinusitis (inflammation of sinus)
Skin infection
Haematochezia (passage of stools containing blood)
Hepatobiliary disease (diseases affect the liver and/or biliary tract)
Pain

30-39:

n/a

40-49:

n/a

50-59:

Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
Small intestinal perforation (hole in small intestine)
Small intestine gangrene (small intestine tissue dies)

60+:

Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Dizziness
Body temperature increased
Central nervous system lymphoma (cancer of central nervous system forms in lymph tissue)
Cholelithiasis obstructive (gall stone obstructs bile ducts)
Confusional state
Constipation
Cough
Death
Depression

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 9 people, 20.45%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 15.91%
High Blood Pressure: 6 people, 13.64%
Pain: 5 people, 11.36%
Immunodeficiency Common Variable: 5 people, 11.36%
Hypokalemia (low potassium): 5 people, 11.36%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 9.09%
Joint Pain: 4 people, 9.09%
Fever: 4 people, 9.09%
Asthma: 4 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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