Pepcid and Lidex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pepcid (famotidine) and Lidex (fluocinonide). Common drug interactions include abdominal pain among females and oedema peripheral among males.

The phase IV clinical study analyzes what interactions people have when they take Pepcid and Lidex. It is created by eHealthMe based on reports of 60 people who take the same drugs from the FDA, and is updated regularly.

What is Pepcid?

Pepcid has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 55,774 Pepcid users. Check the latest studies of Pepcid.

What is Lidex?

Lidex has active ingredients of fluocinonide. eHealthMe is studying from 1,039 Lidex users. Check the latest studies of Lidex.

On Jul, 04, 2026

60 people who take Pepcid and Lidex together, and have interactions are studied.

What are the common drug interactions of Pepcid and Lidex, by gender? *:

female:

Abdominal pain
Arthralgia (joint pain)
Breast calcifications (deposits of calcium that can be seen on a mammogram of the breast)
Breast cyst
Burning sensation
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Confusional state
Deafness
Decreased interest
Depression

male:

Oedema peripheral (superficial swelling)
Rash
Arrhythmia (irregular heartbeat)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac failure congestive
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Death
Drug hypersensitivity
Dupuytren's contracture (thickening of the fibrous tissue layer underneath the skin of the palm and fingers)
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)

What are the common drug interactions of Pepcid and Lidex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal pain
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Abscess jaw (tooth abscess or root abscess)
Anxiety
Arthralgia (joint pain)
Arthropathy
Asthenia (weakness)
Ataxia (loss of full control of bodily movements)
Back pain
Balance disorder

20-29:

Back pain
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Febrile neutropenia (fever with reduced white blood cells)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pulmonary embolism (blockage of the main artery of the lung)
Vomiting

30-39:

Malaise (a feeling of general discomfort or uneasiness)

40-49:

Abdominal pain
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cerebrovascular disorder (disease of brain)
Chest pain
Chronic kidney disease
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Fibromyalgia (a long-term condition which causes pain all over the body)
Gastrointestinal pain
Hypertension (high blood pressure)

50-59:

Syncope (loss of consciousness with an inability to maintain postural tone)
Abdominal distension
Arrhythmia (irregular heartbeat)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac failure congestive
Chills (felling of cold)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Death
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)

60+:

Mobility decreased (ability to move is reduced)
Nausea (feeling of having an urge to vomit)
Erythema (redness of the skin)
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
Impaired healing
Ischaemic ulcer (arterial ulcer)
Joint contracture (a permanent shortening of a muscle or joint)
Joint range of motion decreased (disease of joint movement)
Joint swelling
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)

What are the existing conditions these people have? *

Pain: 19 people, 31.67%
Nausea (feeling of having an urge to vomit): 10 people, 16.67%
Constipation: 9 people, 15.00%
Nausea And Vomiting: 8 people, 13.33%
Wheezing (a high-pitched whistling sound made while you breath): 8 people, 13.33%
Rashes (redness): 8 people, 13.33%
Itching: 7 people, 11.67%
Stress And Anxiety: 7 people, 11.67%
Depression: 6 people, 10.00%
Dissociative Disorder: 5 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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