Pepcid and Northera drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pepcid (famotidine) and Northera (droxidopa). Common drug interactions include viral infection among females and dizziness among males.

The phase IV clinical study analyzes what interactions people have when they take Pepcid and Northera. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Pepcid?

Pepcid has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 55,774 Pepcid users. Check the latest studies of Pepcid.

What is Northera?

Northera has active ingredients of droxidopa. eHealthMe is studying from 22,874 Northera users. Check the latest studies of Northera.

On Jul, 07, 2026

53 people who take Pepcid and Northera together, and have interactions are studied.

What are the common drug interactions of Pepcid and Northera, by gender? *:

female:

Viral infection
Loss of consciousness
Dizziness
Headache (pain in head)
Blood pressure increased
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Urinary tract infection
Abdominal discomfort
Dysstasia (difficulty in standing)
Syncope (loss of consciousness with an inability to maintain postural tone)

male:

Dizziness
Fatigue (feeling of tiredness)
Feeling hot
Headache (pain in head)
Hyperhidrosis (abnormally increased sweating)
Insomnia (sleeplessness)
Malaise (a feeling of general discomfort or uneasiness)
Memory impairment
Palpitations (feelings or sensations that your heart is pounding or racing)
Parkinson's disease

What are the common drug interactions of Pepcid and Northera, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Pain

20-29:

Dizziness
Dyspnoea (difficult or laboured respiration)
Migraine (headache)
Therapeutic response decreased (less preventive response)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Diarrhoea
Hypersensitivity

30-39:

Abdominal discomfort
Diarrhoea
Hypotension (abnormally low blood pressure)
Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Nausea (feeling of having an urge to vomit)
Retching (strong involuntary effort to vomit)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

40-49:

Dysstasia (difficulty in standing)
Loss of consciousness
Syncope (loss of consciousness with an inability to maintain postural tone)
Blood potassium decreased
Dehydration (dryness resulting from the removal of water)
Hereditary angioedema (recurrent episodes of severe swelling)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Staphylococcal infection (an infection with staphylococcus bacteria)
Headache (pain in head)
Localised infection (infection at the single location)

50-59:

Dehydration (dryness resulting from the removal of water)
Diarrhoea
Dizziness
Urinary tract infection

60+:

Dizziness
Blood pressure increased
Abdominal pain
Diarrhoea
Feeling hot
Hyperhidrosis (abnormally increased sweating)
Insomnia (sleeplessness)
Malaise (a feeling of general discomfort or uneasiness)
Memory impairment
Palpitations (feelings or sensations that your heart is pounding or racing)

What are the existing conditions these people have? *

Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 34 people, 64.15%
Parkinson's Disease: 11 people, 20.75%
Autonomic Neuropathy (malfunction of the autonomic nervous system (ans)): 11 people, 20.75%
Fainting (loss of consciousness and postural tone): 4 people, 7.55%
Staphylococcal Infection (an infection with staphylococcus bacteria): 3 people, 5.66%
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 3 people, 5.66%
Hereditary Angioedema (recurrent episodes of severe swelling): 3 people, 5.66%
Bone Density Decreased: 3 people, 5.66%
Autonomic Nervous System Imbalance (autonomic nervous system is of net equal emphasis): 3 people, 5.66%
Asthma: 3 people, 5.66%

* Approximation only. Some reports may have incomplete information.

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