Pepcid and Stromectol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pepcid (famotidine) and Stromectol (ivermectin). Common drug interactions include chronic kidney disease among females and acute respiratory failure among males.

The phase IV clinical study analyzes what interactions people have when they take Pepcid and Stromectol. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Pepcid?

Pepcid has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 55,774 Pepcid users. Check the latest studies of Pepcid.

What is Stromectol?

Stromectol has active ingredients of ivermectin. eHealthMe is studying from 3,361 Stromectol users. Check the latest studies of Stromectol.



On Jul, 11, 2026

14 people who take Pepcid and Stromectol together, and have interactions are studied.

Pepcid and Stromectol drug interactions.

What are the common drug interactions of Pepcid and Stromectol, by gender? *:

female:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  4. Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
  5. Neuropathy peripheral (surface nerve damage)
  6. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  7. Therapeutic response unexpected
  8. Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
  9. Pneumonia

male:

  1. Acute respiratory failure
  2. Hypercalcaemia (elevated calcium (ca+) level in the blood)
  3. Nephrogenic anaemia (anaemia due to kidney disease)
  4. Renal failure (kidney dysfunction)
  5. Alanine aminotransferase increased
  6. Altered state of consciousness (altered state of mind)
  7. Aspartate aminotransferase increased
  8. Atelectasis (partial or complete collapse of the lung)
  9. Blood bilirubin increased
  10. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)

What are the common drug interactions of Pepcid and Stromectol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Chronic kidney disease
  2. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  3. Renal failure (kidney dysfunction)

40-49:

  1. Acute respiratory failure
  2. Renal impairment (severely reduced kidney function)
  3. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  4. Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
  5. Pneumonia
  6. Pyrexia (fever)
  7. Alanine aminotransferase increased
  8. Aspartate aminotransferase increased
  9. Atelectasis (partial or complete collapse of the lung)
  10. Blood bilirubin increased

50-59:

n/a

60+:

  1. Hypercalcaemia (elevated calcium (ca+) level in the blood)
  2. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  3. Gastric disorder (disease of stomach)
  4. Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
  5. Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract)
  6. Pneumonia
  7. Chronic kidney disease
  8. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  9. Nephrogenic anaemia (anaemia due to kidney disease)
  10. Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

  1. High Blood Pressure: 8 people, 57.14%
  2. Acarodermatitis (skin inflammation caused by mites (acarids)): 6 people, 42.86%
  3. Carotid Artery Stenosis (narrowing of carotid artery): 3 people, 21.43%
  4. Constipation: 3 people, 21.43%
  5. Diabetes: 3 people, 21.43%
  6. Dizziness: 3 people, 21.43%
  7. Calculus Urinary (stone in urinary system): 3 people, 21.43%
  8. Gastritis (inflammation of stomach): 3 people, 21.43%
  9. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 3 people, 21.43%
  10. Hyperkalemia (damage to or disease of the kidney): 3 people, 21.43%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Pepcid and Stromectol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pepcid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Stromectol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pepcid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Stromectol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on famotidine and ivermectin (the active ingredients of Pepcid and Stromectol, respectively), and Pepcid and Stromectol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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