Pepcid and Ticagrelor drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Pepcid (famotidine) and Ticagrelor (ticagrelor). Common drug interactions include acute myocardial infarction among females and gastrointestinal haemorrhage among males.
The phase IV clinical study analyzes what interactions people have when they take Pepcid and Ticagrelor. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.
What is Pepcid?
Pepcid has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 55,774 Pepcid users. Check the latest studies of Pepcid.
What is Ticagrelor?
Ticagrelor has active ingredients of ticagrelor. eHealthMe is studying from 8,499 Ticagrelor users. Check the latest studies of Ticagrelor.
15 people who take Pepcid and Ticagrelor together, and have interactions are studied.

What are the common drug interactions of Pepcid and Ticagrelor, by gender? *:
female:
- Acute myocardial infarction (acute heart attack)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Diarrhoea
- Epistaxis (bleed from the nose)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Abdominal distension
- Abdominal pain
- Abdominal pain upper
- Adjustment disorder with disturbance of conduct
- Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
male:
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Coronary artery thrombosis (clot formation in coronary artery)
- Dyspnoea (difficult or laboured respiration)
- Electrocardiogram st segment elevation
- Malaise (a feeling of general discomfort or uneasiness)
- Respiratory distress (difficulty in breathing)
- Ventricular fibrillation (abnormally irregular heart rhythm)
- Ventricular hypokinesia (muscle of one's heart does not contract as much as most peoples' hearts do)
- Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
What are the common drug interactions of Pepcid and Ticagrelor, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Abdominal distension
- Abdominal pain
- Abdominal pain upper
- Acute myocardial infarction (acute heart attack)
- Adjustment disorder with disturbance of conduct
- Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
- Arteriospasm coronary (spasm of the large- or medium-sized coronary arteries)
- Arthralgia (joint pain)
- Back pain
- Blood pressure decreased
50-59:
- Epistaxis (bleed from the nose)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Acute myocardial infarction (acute heart attack)
- Asthenia (weakness)
- Atelectasis (partial or complete collapse of the lung)
- Bronchial hyperreactivity
- Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
- Diarrhoea
60+:
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Malaise (a feeling of general discomfort or uneasiness)
- Respiratory distress (difficulty in breathing)
- Anaemia (lack of blood)
- Constipation
- Hypotension (abnormally low blood pressure)
- Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
- Basal ganglia infarction (disruption of the blood flow in the small blood vessels in the white matter of the cerebral cortex)
- Bradycardia (abnormally slow heart action)
What are the existing conditions these people have? *
- High Blood Pressure: 8 people, 53.33%
- Hyperlipidaemia (presence of excess lipids in the blood): 8 people, 53.33%
- Constipation: 7 people, 46.67%
- Enlarged Prostate: 7 people, 46.67%
- Hypokalemia (low potassium): 6 people, 40.00%
- Indigestion: 6 people, 40.00%
- Type 2 Diabetes: 5 people, 33.33%
- Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 5 people, 33.33%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 33.33%
- Cardiac Failure Congestive: 5 people, 33.33%
* Approximation only. Some reports may have incomplete information.
Do you take Pepcid and Ticagrelor?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Pepcid (55,774 reports)
- Ticagrelor (8,499 reports)
Browse all drug interactions of Pepcid and Ticagrelor:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Pepcid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ticagrelor:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pepcid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ticagrelor and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on famotidine and ticagrelor (the active ingredients of Pepcid and Ticagrelor, respectively), and Pepcid and Ticagrelor (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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