Pepcid and Trelstar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pepcid (famotidine) and Trelstar (triptorelin pamoate). Common drug interactions include anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Pepcid and Trelstar. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Pepcid?

Pepcid has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 55,774 Pepcid users. Check the latest studies of Pepcid.

What is Trelstar?

Trelstar has active ingredients of triptorelin pamoate. eHealthMe is studying from 1,506 Trelstar users. Check the latest studies of Trelstar.



On Jul, 26, 2026

19 people who take Pepcid and Trelstar together, and have interactions are studied.

Pepcid and Trelstar drug interactions.

What are the common drug interactions of Pepcid and Trelstar, by gender? *:

female:

n/a

male:

  1. Anxiety
  2. Dyspnoea (difficult or laboured respiration)
  3. Erectile dysfunction
  4. Haemorrhoids (a swollen vein or group of veins in the region of the anus)
  5. Hilar lymphadenopathy (disease of the lymph nodes due to infection)
  6. Injury
  7. Intervertebral disc degeneration (spinal disc degeneration)
  8. Intervertebral disc protrusion (spinal disc protrusion)
  9. Lymphadenopathy mediastinal (an enlargement of the lymph nodes in the part of the chest that separates the lungs)
  10. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)

What are the common drug interactions of Pepcid and Trelstar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Asthenia (weakness)
  2. Colon cancer metastatic (cancer of colon spreads to other part of body)
  3. Dyspnoea exertional (breathlessness or shortness of breath)
  4. Fatigue (feeling of tiredness)
  5. Heart rate increased
  6. Oedema peripheral (superficial swelling)
  7. Pain

50-59:

  1. Death
  2. Diastolic dysfunction
  3. Diplopia (double vision)
  4. Disability
  5. Dizziness
  6. Dry eye (lack of adequate tears)
  7. Dyslipidaemia (abnormal amount of lipids)
  8. Dysphagia (a condition in which swallowing is difficult or painful)
  9. Dysphonia (speech disorder attributable to a disorder of phonation)
  10. Dyspnoea (difficult or laboured respiration)

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Anaemia (lack of blood)
  3. Hilar lymphadenopathy (disease of the lymph nodes due to infection)
  4. Injury
  5. Intervertebral disc degeneration (spinal disc degeneration)
  6. Intervertebral disc protrusion (spinal disc protrusion)
  7. Lymphadenopathy mediastinal (an enlargement of the lymph nodes in the part of the chest that separates the lungs)
  8. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  9. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  10. Neoplasm malignant (cancer tumour)

What are the existing conditions these people have? *

  1. Prostate Cancer: 12 people, 63.16%
  2. Osteoporosis (bones weak and more likely to break): 4 people, 21.05%
  3. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 10.53%
  4. Rectal Cancer (cancer of rectum): 1 person, 5.26%
  5. Prostate Cancer Metastatic: 1 person, 5.26%
  6. Neuromyelitis Optica (inflammation and demyelination of the optic nerve (optic neuritis) and the spinal cord (myelitis)): 1 person, 5.26%
  7. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 5.26%
  8. High Blood Pressure: 1 person, 5.26%
  9. High Blood Cholesterol: 1 person, 5.26%
  10. Hepatitis C: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Pepcid and Trelstar?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Pepcid and Trelstar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pepcid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Trelstar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pepcid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Trelstar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on famotidine and triptorelin pamoate (the active ingredients of Pepcid and Trelstar, respectively), and Pepcid and Trelstar (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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