Pepcid and Zortress drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pepcid (famotidine) and Zortress (everolimus). Common drug interactions include vomiting among females and cough among males.

The phase IV clinical study analyzes what interactions people have when they take Pepcid and Zortress. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Pepcid?

Pepcid has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 55,774 Pepcid users. Check the latest studies of Pepcid.

What is Zortress?

Zortress has active ingredients of everolimus. eHealthMe is studying from 1,589 Zortress users. Check the latest studies of Zortress.

On Aug, 04, 2026

13 people who take Pepcid and Zortress together, and have interactions are studied.

What are the common drug interactions of Pepcid and Zortress, by gender? *:

female:

Vomiting
Abdominal pain
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Nausea (feeling of having an urge to vomit)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Acute respiratory failure
Anaemia (lack of blood)
Blood disorder
Cardiac failure congestive

male:

Cough
Insomnia (sleeplessness)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Concomitant disease progression (progress in accompanying disease)
Dysgeusia (disorder of the sense of taste)
Inguinal hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)
Left ventricular dysfunction
Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Lymphoma (cancer that begins in immune system cells)
Mitral valve incompetence (inefficient heart valve)

What are the common drug interactions of Pepcid and Zortress, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Vomiting
Abdominal pain
Liver disorder (liver diseases)
Back pain
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Febrile neutropenia (fever with reduced white blood cells)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

30-39:

n/a

40-49:

Arthralgia (joint pain)
Disease progression
Drug abuse
Hepatic fibrosis (scarring process that represents the liver's response to injury)
Hepatitis c
Liver transplant rejection (failure of liver transplant)
Peripheral swelling
Swollen tongue (swelling of tongue)

50-59:

Aneurysm (enlargement of an artery caused by a weakening of the artery wall)
Aortic valve incompetence
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cough
Inguinal hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)
Insomnia (sleeplessness)
Left ventricular dysfunction
Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Mitral valve incompetence (inefficient heart valve)
Mitral valve stenosis (narrowing of mitral valve)

60+:

Chronic kidney disease
Proteinuria (presence of protein in the urine)
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Frequent bowel movements
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hypertension (high blood pressure)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Joint swelling
Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

Immunodeficiency Disorders: 6 people, 46.15%
Nausea (feeling of having an urge to vomit): 3 people, 23.08%
Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 3 people, 23.08%
Vasculitis (inflammation of a blood vessel or blood vessels): 2 people, 15.38%
Constipation: 2 people, 15.38%
Urinary Tract Infection: 1 person, 7.69%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 7.69%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 7.69%
Pain: 1 person, 7.69%
Indigestion: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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