Perampanel and Ibu drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Perampanel (perampanel) and Ibu (ibuprofen). Common drug interactions include adjustment disorder with depressed mood among females and aggression among males.

The phase IV clinical study analyzes what interactions people have when they take Perampanel and Ibu. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Perampanel?

Perampanel has active ingredients of perampanel. eHealthMe is studying from 2,474 Perampanel users. Check the latest studies of Perampanel.

What is Ibu?

Ibu has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 246,531 Ibu users. Check the latest studies of Ibu.

On Jul, 26, 2026

16 people who take Perampanel and Ibu together, and have interactions are studied.

What are the common drug interactions of Perampanel and Ibu, by gender? *:

female:

Adjustment disorder with depressed mood
Dizziness
Encephalopathy (functioning of the brain is affected by some agent or condition)
Fatigue (feeling of tiredness)
Gastroenteritis (inflammation of stomach and intestine)
Somnolence (a state of near-sleep, a strong desire for sleep)
Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
Cerebral disorder (brain disease)
Suicide attempt
General physical health deterioration (weak health status)

male:

Aggression
Alanine aminotransferase increased
Aspartate aminotransferase increased
Chronic kidney disease
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hospitalisation
Renal failure (kidney dysfunction)

What are the common drug interactions of Perampanel and Ibu, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Aggression
Alanine aminotransferase increased
Aspartate aminotransferase increased

20-29:

Abdominal pain upper

30-39:

General physical health deterioration (weak health status)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Suicide attempt

40-49:

Adjustment disorder with depressed mood
Dizziness
Fatigue (feeling of tiredness)
Somnolence (a state of near-sleep, a strong desire for sleep)
Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)

50-59:

n/a

60+:

Encephalopathy (functioning of the brain is affected by some agent or condition)
Gastroenteritis (inflammation of stomach and intestine)
Chronic kidney disease
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

Partial Seizures (seizures which affect only a part of the brain at onset): 9 people, 56.25%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 9 people, 56.25%
Infection: 6 people, 37.50%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 12.50%
Sleep Disorder: 1 person, 6.25%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.25%
Affective Disorder (mental disorder): 1 person, 6.25%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 6.25%
Constipation: 1 person, 6.25%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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