Percocet and Celestone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Percocet (acetaminophen; oxycodone hydrochloride) and Celestone (betamethasone). Common drug interactions include metastases to spine among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Percocet and Celestone. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.

What is Percocet?

Percocet has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 119,838 Percocet users. Check the latest studies of Percocet.

What is Celestone?

Celestone has active ingredients of betamethasone. It is often used in bursitis. eHealthMe is studying from 1,788 Celestone users. Check the latest studies of Celestone.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

51 people who take Percocet and Celestone together, and have interactions are studied.

Percocet and Celestone drug interactions.

What are the common drug interactions of Percocet and Celestone, by gender? *:

female:

Metastases to spine (cancer spreads to spine)
Mobility decreased (ability to move is reduced)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Pain in extremity
Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)
Spinal column stenosis (narrowing of spinal column)
Spinal osteoarthritis (joint cartilage loss in spine)
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Colonic polyp (extra part of colon tissue grow in intestine)
Decreased appetite

male:

Anaemia (lack of blood)
Asthenia (weakness)
Tenderness (pain or discomfort when an affected area is touched)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Bone disorder
Breast mass
Calculus ureteric (stone in ureter)
Costochondritis (chest wall pain)
Dental caries
Disability

What are the common drug interactions of Percocet and Celestone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Constipation
Depression
Drug abuser
Drug dependence
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Insomnia (sleeplessness)
Hypoaesthesia (reduced sense of touch or sensation)
Aggression
Atelectasis (partial or complete collapse of the lung)
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)

40-49:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Anxiety
Asthenia (weakness)
Chills (felling of cold)
Cyst (a closed sac)
Depression
Drug abuser
Drug dependence
Drug ineffective

50-59:

Urinary incontinence (inability to control the flow of urine and involuntary urination)
Aggression
Anaemia (lack of blood)
Asthenia (weakness)
Cytomegalovirus infection
Diarrhoea
Dizziness
Facial bones fracture (bone fracture of face)
Fatigue (feeling of tiredness)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Compression fracture (fracture due to pressure caused by injury)
Constipation
Hypotension (abnormally low blood pressure)
Arthralgia (joint pain)
Fall
Gynaecomastia (enlargement of the gland tissue of the male breast)
Hypoaesthesia (reduced sense of touch or sensation)
Injury

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 9 people, 17.65%
Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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