Percocet and Copegus drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Percocet (acetaminophen; oxycodone hydrochloride) and Copegus (ribavirin). Common drug interactions include alopecia among females and insomnia among males.

The phase IV clinical study analyzes what interactions people have when they take Percocet and Copegus. It is created by eHealthMe based on reports of 74 people who take the same drugs from the FDA, and is updated regularly.

What is Percocet?

Percocet has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 119,838 Percocet users. Check the latest studies of Percocet.

What is Copegus?

Copegus has active ingredients of ribavirin. It is often used in hepatitis c. eHealthMe is studying from 15,115 Copegus users. Check the latest studies of Copegus.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

74 people who take Percocet and Copegus together, and have interactions are studied.

What are the common drug interactions of Percocet and Copegus, by gender? *:

female:

Alopecia (absence of hair from areas of the body)
Dyspnoea (difficult or laboured respiration)
Arthralgia (joint pain)
Dry skin
Headache (pain in head)
Rash
Chest pain
Depression
Haemoglobin decreased
Insomnia (sleeplessness)

male:

Insomnia (sleeplessness)
Abdominal pain
Depression
Alopecia (absence of hair from areas of the body)
Dry eye (lack of adequate tears)
Energy increased
Flatulence (flatus expelled through the anus)
Full blood count decreased
Hallucination (an experience involving the perception of something not present)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)

What are the common drug interactions of Percocet and Copegus, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anxiety
Depression
Dyspnoea (difficult or laboured respiration)
Hallucination, auditory (perceiving sounds without auditory stimulus)
Hallucination, visual (seeing things that aren't there)
Liver disorder (liver diseases)
Mood swings (an extreme or rapid change in mood)
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Psychotic disorder
Skin lesion

30-39:

n/a

40-49:

Diarrhoea
Weight decreased
Insomnia (sleeplessness)
Alopecia (absence of hair from areas of the body)
Rash
Arthralgia (joint pain)
Headache (pain in head)
Depression
Irritability
White blood cell count decreased

50-59:

Asthma
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood triglycerides increased
Body temperature fluctuation
Cerebral haemorrhage (bleeding within the brain)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Depression
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Drug ineffective
Hyperhidrosis (abnormally increased sweating)

60+:

Abdominal pain
Anaemia (lack of blood)
Decreased appetite
Depression
Dysgeusia (disorder of the sense of taste)
Eating disorder
Erythema (redness of the skin)
Face oedema (swelling of face)
Fatigue (feeling of tiredness)
Food aversion (we reject certain foods for a reason)

What are the existing conditions these people have? *

Depression: 24 people, 32.43%
Back Pain: 16 people, 21.62%
Stress And Anxiety: 12 people, 16.22%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 8 people, 10.81%
Sleep Disorder: 6 people, 8.11%
Anaemia (lack of blood): 5 people, 6.76%

* Approximation only. Some reports may have incomplete information.

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