Periactin and Bactroban drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Periactin (cyproheptadine hydrochloride) and Bactroban (mupirocin). Common drug interactions include pyrexia among females and acute respiratory failure among males.

The phase IV clinical study analyzes what interactions people have when they take Periactin and Bactroban. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Periactin?

Periactin has active ingredients of cyproheptadine hydrochloride. It is often used in migraine. eHealthMe is studying from 2,214 Periactin users. Check the latest studies of Periactin.

What is Bactroban?

Bactroban has active ingredients of mupirocin. It is often used in infection. eHealthMe is studying from 4,967 Bactroban users. Check the latest studies of Bactroban.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

19 people who take Periactin and Bactroban together, and have interactions are studied.

Periactin and Bactroban drug interactions.

What are the common drug interactions of Periactin and Bactroban, by gender? *:

female:

Pyrexia (fever)
Asthma
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Cystic fibrosis (disease of the secretary glands)
Headache (pain in head)
Insomnia (sleeplessness)
Peritonitis bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial)
Visual acuity reduced (reduced clearness of vision)

male:

Acute respiratory failure
Pyrexia (fever)
Dyspnoea (difficult or laboured respiration)
Feeling hot
Flushing (the warm, red condition of human skin)
Influenza
Infusion site pain
Pneumonia
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Pulmonary oedema (fluid accumulation in the lungs)

What are the common drug interactions of Periactin and Bactroban, by age (0-1 to 60+)? *:

0-1:

Acute respiratory failure
Pyrexia (fever)
Bronchiolitis (inflammation of the membranes lining the bronchioles in lungs)
Catheter site discharge
Catheter site haemorrhage (bleeding at catheter site)
Catheter site pain
Catheter site swelling
Corona virus infection (infection caused by a corona virus)
Dyspnoea (difficult or laboured respiration)
Feeling hot

2-9:

Asthma
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Pyrexia (fever)
Cystic fibrosis (disease of the secretary glands)
Peritonitis bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial)
Visual acuity reduced (reduced clearness of vision)

10-19:

Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Agitation (state of anxiety or nervous excitement)
Atrophy (wasting away of a part of the body)
Bone formation increased
Cardiac failure
Constipation
Headache (pain in head)
Implant site pain
Insomnia (sleeplessness)
Irritability

20-29:

n/a

30-39:

Application site erythema (redness of the skin at application site)
Application site pain
Application site rash
Application site urticaria
Application site vesicles (small bubble within a cell at application site)
Headache (pain in head)
Insomnia (sleeplessness)

40-49:

n/a

50-59:

Dyslipidaemia (abnormal amount of lipids)
Hypertension (high blood pressure)
Lymphoedema (localized fluid retention and tissue swelling)
Narcolepsy (brain's inability to regulate sleep-wake cycles normally)
Nipple exudate bloody (discharge from nipple with blood)
Overweight
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Type 2 diabetes mellitus
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)

60+:

Cardiac failure congestive
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Hyperhidrosis (abnormally increased sweating)
Inferior vena caval occlusion
Pain in extremity
Pulmonary oedema (fluid accumulation in the lungs)
Renal failure chronic (long lasting kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)

What are the existing conditions these people have? *

Asthma: 6 people, 31.58%
Cystic Fibrosis (disease of the secretary glands): 5 people, 26.32%
High Blood Pressure: 3 people, 15.79%
Allergic Rhinitis: 3 people, 15.79%
Fungal Infection: 3 people, 15.79%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 15.79%
Infective Pulmonary Exacerbation Of Cystic Fibrosis (severe infective lung disease with production of abnormally thick mucus): 3 people, 15.79%
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 3 people, 15.79%
Muscle Spasms (muscle contraction): 2 people, 10.53%
Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon): 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

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