Peridex and Bentyl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Peridex (chlorhexidine gluconate) and Bentyl (dicyclomine hydrochloride). Common drug interactions include urinary tract infection among females and venoocclusive liver disease among males.

The phase IV clinical study analyzes what interactions people have when they take Peridex and Bentyl. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Peridex?

Peridex has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 2,803 Peridex users. Check the latest studies of Peridex.

What is Bentyl?

Bentyl has active ingredients of dicyclomine hydrochloride. It is often used in irritable bowel syndrome. eHealthMe is studying from 10,754 Bentyl users. Check the latest studies of Bentyl.



On Jul, 20, 2026

23 people who take Peridex and Bentyl together, and have interactions are studied.

Peridex and Bentyl drug interactions.

What are the common drug interactions of Peridex and Bentyl, by gender? *:

female:

  1. Urinary tract infection
  2. Anal inflammation
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Anxiety
  5. Arteriosclerosis (thickening and hardening of arteries)
  6. Arthralgia (joint pain)
  7. Arthropathy
  8. Atelectasis (partial or complete collapse of the lung)
  9. Atrioventricular block first degree (heart block first degree)
  10. Blood glucose increased

male:

  1. Venoocclusive liver disease (small veins in the liver are obstructed)

What are the common drug interactions of Peridex and Bentyl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Hyperbilirubinaemia (excess of bilirubin in the blood)
  2. Abdominal discomfort
  3. Antinuclear antibody positive
  4. Colitis (inflammation of colon)
  5. Diarrhoea
  6. Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
  7. Dyspnoea (difficult or laboured respiration)
  8. Generalised oedema (swelling all over the body)
  9. Oliguria (not enough urine)
  10. Thrombocytopenia (decrease of platelets in blood)

50-59:

  1. Anaemia (lack of blood)
  2. Anal inflammation
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Anxiety
  5. Arteriosclerosis (thickening and hardening of arteries)
  6. Arthralgia (joint pain)
  7. Arthropathy
  8. Atelectasis (partial or complete collapse of the lung)
  9. Atrioventricular block first degree (heart block first degree)
  10. Blood glucose increased

60+:

  1. Osteonecrosis of jaw (death of bone of jaw)
  2. Urinary tract infection
  3. Asthenia (weakness)
  4. Atelectasis (partial or complete collapse of the lung)
  5. Atrioventricular block first degree (heart block first degree)
  6. Blood glucose increased
  7. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  8. Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
  9. Cardiac aneurysm (a condition that can occur after a myocardial infarction due to the inadequate resistance of the new scar tissue to the systolic pressure)
  10. Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)

What are the existing conditions these people have? *

  1. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 5 people, 21.74%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 21.74%
  3. Nausea (feeling of having an urge to vomit): 5 people, 21.74%
  4. High Blood Pressure: 5 people, 21.74%
  5. Leukocytosis (increased white blood cells): 4 people, 17.39%
  6. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 4 people, 17.39%
  7. Constipation: 4 people, 17.39%
  8. Diarrhea: 4 people, 17.39%
  9. Febrile Neutropenia (fever with reduced white blood cells): 4 people, 17.39%
  10. Fluid Overload (too much fluid in the blood): 4 people, 17.39%

* Approximation only. Some reports may have incomplete information.

Do you take Peridex and Bentyl?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Peridex and Bentyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Peridex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Bentyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Peridex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bentyl and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on chlorhexidine gluconate and dicyclomine hydrochloride (the active ingredients of Peridex and Bentyl, respectively), and Peridex and Bentyl (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: