Peridex and Vimpat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Peridex (chlorhexidine gluconate) and Vimpat (lacosamide). Common drug interactions include burning sensation among females and coma among males.

The phase IV clinical study analyzes what interactions people have when they take Peridex and Vimpat. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Peridex?

Peridex has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 2,803 Peridex users. Check the latest studies of Peridex.

What is Vimpat?

Vimpat has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 20,832 Vimpat users. Check the latest studies of Vimpat.



On Aug, 10, 2026

13 people who take Peridex and Vimpat together, and have interactions are studied.

Peridex and Vimpat drug interactions.

What are the common drug interactions of Peridex and Vimpat, by gender? *:

female:

  1. Burning sensation
  2. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  3. Fall
  4. Haemorrhage intracranial (bleeding within the skull)
  5. Hyperbilirubinaemia (excess of bilirubin in the blood)
  6. Hypertension (high blood pressure)
  7. Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
  8. Hypokalaemia (low potassium)
  9. Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
  10. Nausea (feeling of having an urge to vomit)

male:

  1. Coma (state of unconsciousness lasting more than six hours)
  2. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  3. Bradycardia (abnormally slow heart action)
  4. Cytokine storm (over-protective immune response that can actually be fatal)
  5. Fungaemia (fungi circulate in the blood)
  6. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  7. Haematuria (presence of blood in urine)
  8. Hyperkalaemia (damage to or disease of the kidney)
  9. Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
  10. Hypocalcaemia (levels of calcium in blood serum are abnormally low)

What are the common drug interactions of Peridex and Vimpat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent)
  2. Blood creatinine increased
  3. Blood lactic acid increased
  4. Blood urea increased
  5. Bone marrow failure
  6. Bradycardia (abnormally slow heart action)
  7. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  8. Cytokine storm (over-protective immune response that can actually be fatal)
  9. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  10. Haematuria (presence of blood in urine)

20-29:

n/a

30-39:

  1. Aggression
  2. Anticonvulsant drug level increased

40-49:

  1. Fall
  2. Haemorrhage intracranial (bleeding within the skull)
  3. Hyperbilirubinaemia (excess of bilirubin in the blood)
  4. Hypertension (high blood pressure)
  5. Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
  6. Hypokalaemia (low potassium)
  7. Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
  8. Memory impairment
  9. Burning sensation
  10. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)

50-59:

n/a

60+:

  1. Coma (state of unconsciousness lasting more than six hours)
  2. Nausea (feeling of having an urge to vomit)
  3. Tremor (trembling or shaking movements in one or more parts of your body)
  4. Arthralgia (joint pain)
  5. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  6. Disease progression
  7. Fatigue (feeling of tiredness)
  8. Fungaemia (fungi circulate in the blood)

What are the existing conditions these people have? *

  1. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 4 people, 30.77%
  2. Pain: 3 people, 23.08%
  3. Constipation: 3 people, 23.08%
  4. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 15.38%
  5. Lennox-Gastaut Syndrome (epilepsy characterized by frequent seizures and different seizure types): 2 people, 15.38%
  6. Fever: 2 people, 15.38%
  7. Wheezing (a high-pitched whistling sound made while you breath): 1 person, 7.69%
  8. Gingivitis (inflammation of gums): 1 person, 7.69%
  9. Arrhythmias (irregular heartbeat): 1 person, 7.69%
  10. Cough: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Peridex and Vimpat?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Peridex and Vimpat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Peridex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Vimpat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Peridex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vimpat and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on chlorhexidine gluconate and lacosamide (the active ingredients of Peridex and Vimpat, respectively), and Peridex and Vimpat (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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