Periogard and Azithromycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Periogard (chlorhexidine gluconate) and Azithromycin (azithromycin). Common drug interactions include impaired healing among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Periogard and Azithromycin. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Periogard?

Periogard has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 3,814 Periogard users. Check the latest studies of Periogard.

What is Azithromycin?

Azithromycin has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 40,716 Azithromycin users. Check the latest studies of Azithromycin.

On Jul, 14, 2026

36 people who take Periogard and Azithromycin together, and have interactions are studied.

Periogard and Azithromycin drug interactions.

What are the common drug interactions of Periogard and Azithromycin, by gender? *:

female:

Impaired healing
Tooth extraction
Skin papilloma (a general medical term for a tumour of the skin or mucous membrane with finger-like projections)
Anaemia (lack of blood)
Decreased interest
Fall
Femur fracture
General physical health deterioration (weak health status)
Loose tooth
Osteoporosis (bones weak and more likely to break)

male:

Dyspnoea (difficult or laboured respiration)
Osteonecrosis of jaw (death of bone of jaw)
Nausea (feeling of having an urge to vomit)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Pyrexia (fever)
Thrombocytopenia (decrease of platelets in blood)
Asthenia (weakness)
Bone fragmentation
Dental caries
Dry mouth

What are the common drug interactions of Periogard and Azithromycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Actinic keratosis (skin disease due to sun exposure)
Adenomyosis (presence of ectopic glandular tissue found in muscle)
Anaemia (lack of blood)
Anxiety
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Balance disorder
Bone density increased
Bone disorder
Calcinosis (calcium deposits in any soft tissue)
Cardiac arrest

20-29:

n/a

30-39:

n/a

40-49:

Anxiety
Pain
Anaemia (lack of blood)
Injury
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Tooth extraction
Ascites (accumulation of fluid in the abdominal cavity)
Bone disorder
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Hypoaesthesia (reduced sense of touch or sensation)

50-59:

Constipation
Diarrhoea
Dizziness
Fatigue (feeling of tiredness)
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hepatic steatosis (fatty liver disease)
Injury
Intervertebral disc protrusion (spinal disc protrusion)
Metastases to bone (cancer spreads to bone)

60+:

Bone disorder
Fall
Femur fracture
General physical health deterioration (weak health status)
Osteoradionecrosis (irradiation of bones causes damage to osteocytes and impairs the blood supply)
Pain
Photopsia (presence of perceived flashes of light)
Posterior capsule opacification
Skin papilloma (a general medical term for a tumour of the skin or mucous membrane with finger-like projections)
Tooth disorder (tooth disease)

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 5 people, 13.89%

* Approximation only. Some reports may have incomplete information.

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