Periostat and Colace drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Periostat (doxycycline hyclate) and Colace (docusate ). Common drug interactions include pseudomonas infection among females and acute prerenal failure among males.
The phase IV clinical study analyzes what interactions people have when they take Periostat and Colace. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.
What is Periostat?
Periostat has active ingredients of doxycycline hyclate. eHealthMe is studying from 273 Periostat users. Check the latest studies of Periostat.
What is Colace?
Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,841 Colace users. Check the latest studies of Colace.
21 people who take Periostat and Colace together, and have interactions are studied.

What are the common drug interactions of Periostat and Colace, by gender? *:
female:
- Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
- Pulmonary mass
- Rash macular (small, flat red spots)
- Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
- Rash pruritic (redness with itching)
- Respiratory disorder (respiratory disease)
- Sinusitis (inflammation of sinus)
- Spinal compression fracture (fracture due to spinal compression on bone)
- Vaginal infection
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
male:
- Acute prerenal failure (prerenal acute renal failure (arf) occurs when a sudden reduction in blood flow to the kidney)
- Anaemia (lack of blood)
- Cardiac failure congestive
- Carotid artery disease
- Cerebral haemorrhage (bleeding within the brain)
- Compression fracture (fracture due to pressure caused by injury)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Delusion (a false belief or opinion)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Dysphagia (a condition in which swallowing is difficult or painful)
What are the common drug interactions of Periostat and Colace, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Atrioventricular block first degree (heart block first degree)
- Back pain
- Bladder outlet obstruction (urological condition where the urine flow from the urinary bladder through the urethra is impeded)
- Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
- Brain injury
- Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
- Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
- Calculus ureteric (stone in ureter)
- Cardiac failure congestive
- Cardiomegaly (increased size of heart than normal)
50-59:
n/a
60+:
- Anaemia (lack of blood)
- Anxiety
- Breath odour
- Cataract (clouding of the lens inside the eye)
- Chest pain
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
- Contusion (a type of hematoma of tissue in which capillaries)
- Dental caries
- Dyspnoea (difficult or laboured respiration)
What are the existing conditions these people have? *
- Stress And Anxiety: 18 people, 85.71%
- Metastases To Bone (cancer spreads to bone): 18 people, 85.71%
* Approximation only. Some reports may have incomplete information.
Do you take Periostat and Colace?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Periostat and Colace:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Periostat:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Colace:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Periostat and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Colace and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on doxycycline hyclate and docusate (the active ingredients of Periostat and Colace, respectively), and Periostat and Colace (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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