Perjeta and Emla drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Perjeta (pertuzumab) and Emla (lidocaine; prilocaine). Common drug interactions include alopecia among females.

The phase IV clinical study analyzes what interactions people have when they take Perjeta and Emla. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Perjeta?

Perjeta has active ingredients of pertuzumab. eHealthMe is studying from 13,388 Perjeta users. Check the latest studies of Perjeta.

What is Emla?

Emla has active ingredients of lidocaine; prilocaine. eHealthMe is studying from 5,276 Emla users. Check the latest studies of Emla.

On Jul, 10, 2026

41 people who take Perjeta and Emla together, and have interactions are studied.

What are the common drug interactions of Perjeta and Emla, by gender? *:

female:

Alopecia (absence of hair from areas of the body)
Diarrhoea
Alopecia areata (patchy baldness that typically begins with rapid hair loss)
Back pain
Decreased appetite
Metastases to lymph nodes (cancer spreads to lymph node)
Abdominal pain
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Weight decreased

male:

n/a

What are the common drug interactions of Perjeta and Emla, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Alopecia areata (patchy baldness that typically begins with rapid hair loss)
Alopecia totalis (loss of all head hair)
Constipation
Decreased appetite
Diarrhoea
Hair colour changes
Motion sickness (travel sickness)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Proctalgia (pain in the rectum)
Vomiting

30-39:

Alopecia (absence of hair from areas of the body)
Abdominal pain
Anaemia (lack of blood)
Cardiac arrest
Cardiomegaly (increased size of heart than normal)
Chest pain
Fatigue (feeling of tiredness)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)
Myocarditis (inflammation of heart muscle myocardium)

40-49:

Alopecia (absence of hair from areas of the body)
Hair colour changes
Hair disorder
Fatigue (feeling of tiredness)
Chest pain
Dyspnoea (difficult or laboured respiration)
Psychological trauma
Blepharospasm (any abnormal contraction or twitch of the eyelid)
Catheter site erythema (redness of skin at catheter site)
Catheter site pain

50-59:

Cellulitis (infection under the skin)
Cough
Decreased appetite
Device related infection
Diverticulum gastric (sensation of fullness in the upper abdomen immediately after meals)
Ejection fraction decreased (systolic heart failure)
Escherichia bacteraemia (presence of bacteria escherichia coli in the blood)
Gallbladder enlargement
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hair colour changes

60+:

Hair colour changes
Alopecia (absence of hair from areas of the body)
Nausea (feeling of having an urge to vomit)
Neoplasm progression (growth of tumour)
Oral infection
Abdominal distension
Abdominal mass (localized enlargement or swelling in the human abdomen)
Alopecia areata (patchy baldness that typically begins with rapid hair loss)
Anaemia (lack of blood)
Anxiety

What are the existing conditions these people have? *

Breast Cancer Female: 13 people, 31.71%
Pain: 10 people, 24.39%
Breast Cancer Metastatic: 9 people, 21.95%
Breast Cancer: 8 people, 19.51%
Nausea (feeling of having an urge to vomit): 7 people, 17.07%
Stress And Anxiety: 5 people, 12.20%
Metastases To Bone (cancer spreads to bone): 4 people, 9.76%
Diarrhea: 4 people, 9.76%
Nausea And Vomiting: 3 people, 7.32%
Muscle Spasms (muscle contraction): 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

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