Perjeta and Pepcid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Perjeta (pertuzumab) and Pepcid (famotidine). Common drug interactions include hair colour changes among females.

The phase IV clinical study analyzes what interactions people have when they take Perjeta and Pepcid. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Perjeta?

Perjeta has active ingredients of pertuzumab. eHealthMe is studying from 13,388 Perjeta users. Check the latest studies of Perjeta.

What is Pepcid?

Pepcid has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 55,774 Pepcid users. Check the latest studies of Pepcid.

On Jul, 15, 2026

49 people who take Perjeta and Pepcid together, and have interactions are studied.

What are the common drug interactions of Perjeta and Pepcid, by gender? *:

female:

Hair colour changes
Alopecia (absence of hair from areas of the body)
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Rash
Constipation
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Chills (felling of cold)
Motion sickness (travel sickness)
Proctalgia (pain in the rectum)

male:

n/a

What are the common drug interactions of Perjeta and Pepcid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Alopecia areata (patchy baldness that typically begins with rapid hair loss)
Alopecia totalis (loss of all head hair)
Constipation
Decreased appetite
Diarrhoea
Hair colour changes
Motion sickness (travel sickness)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Proctalgia (pain in the rectum)
Vomiting

30-39:

Alopecia (absence of hair from areas of the body)
Flushing (the warm, red condition of human skin)
Hair colour changes
Hair disorder
Rash
Urticaria (rash of round, red welts on the skin that itch intensely)
Psychological trauma

40-49:

Fatigue (feeling of tiredness)
Abdominal pain
Alopecia (absence of hair from areas of the body)
Chills (felling of cold)
Dacryostenosis acquired (obstruction of the nasolacrimal duct-acquired)
Lacrimation increased
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Sneezing
Vomiting

50-59:

Alopecia (absence of hair from areas of the body)
Hair colour changes
Hair disorder
Diarrhoea
Nausea (feeling of having an urge to vomit)
Rash
Alopecia areata (patchy baldness that typically begins with rapid hair loss)
Alopecia totalis (loss of all head hair)
Fatigue (feeling of tiredness)
Vomiting

60+:

Alopecia (absence of hair from areas of the body)
Diarrhoea
Chest pain
Chills (felling of cold)
Cough
Decreased appetite
Dehydration (dryness resulting from the removal of water)
Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)
Epistaxis (bleed from the nose)

What are the existing conditions these people have? *

Breast Cancer Female: 15 people, 30.61%
Breast Cancer: 13 people, 26.53%
Breast Cancer Metastatic: 9 people, 18.37%
Stress And Anxiety: 3 people, 6.12%

* Approximation only. Some reports may have incomplete information.

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