Perjeta and Prilosec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Perjeta (pertuzumab) and Prilosec (omeprazole). Common drug interactions include fatigue among females and chest pain among males.

The phase IV clinical study analyzes what interactions people have when they take Perjeta and Prilosec. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Perjeta?

Perjeta has active ingredients of pertuzumab. eHealthMe is studying from 13,388 Perjeta users. Check the latest studies of Perjeta.

What is Prilosec?

Prilosec has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 175,285 Prilosec users. Check the latest studies of Prilosec.

On Jul, 17, 2026

16 people who take Perjeta and Prilosec together, and have interactions are studied.

What are the common drug interactions of Perjeta and Prilosec, by gender? *:

female:

Fatigue (feeling of tiredness)
Alopecia areata (patchy baldness that typically begins with rapid hair loss)
Chest pain
Dyspnoea (difficult or laboured respiration)
Hair colour changes
Asthenia (weakness)
Back pain
Cellulitis (infection under the skin)
Decreased appetite
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

male:

Chest pain
Fatigue (feeling of tiredness)
Haemoglobin decreased
Malignant neoplasm progression (cancer tumour came back)
Metastases to skin (cancer spreads to skin)
Oral candidiasis (fungal infection of mouth)
Wound
Wound haemorrhage (bleeding wound)

What are the common drug interactions of Perjeta and Prilosec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chest pain
Fatigue (feeling of tiredness)
Haemoglobin decreased
Malignant neoplasm progression (cancer tumour came back)
Metastases to skin (cancer spreads to skin)
Oral candidiasis (fungal infection of mouth)
Wound
Wound haemorrhage (bleeding wound)

40-49:

Dyspnoea (difficult or laboured respiration)
Abdominal pain
Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Acute myocardial infarction (acute heart attack)
Chest pain
Coronary artery embolism (blockage of artery of heart)
Dry eye (lack of adequate tears)
Eye irritation
Eye pain
Eye pruritus (eye itching)

50-59:

Alopecia areata (patchy baldness that typically begins with rapid hair loss)
Hair colour changes
Alopecia (absence of hair from areas of the body)
Bone density decreased
Upper limb fracture

60+:

Alopecia (absence of hair from areas of the body)
Back pain
Pruritus (severe itching of the skin)
Rash
Anxiety
Emotional distress
Cellulitis (infection under the skin)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diarrhoea
Fall

What are the existing conditions these people have? *

Breast Cancer: 7 people, 43.75%
Breast Cancer Female: 6 people, 37.50%
Pain: 6 people, 37.50%
Nausea (feeling of having an urge to vomit): 4 people, 25.00%
Breast Cancer Metastatic: 3 people, 18.75%
Nausea And Vomiting: 3 people, 18.75%
Constipation: 2 people, 12.50%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 6.25%
High Blood Cholesterol: 1 person, 6.25%
Asthma: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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