Permax and Famotidine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Permax (pergolide mesylate) and Famotidine (famotidine). Common drug interactions include coma among females and aortic valve incompetence among males.

The phase IV clinical study analyzes what interactions people have when they take Permax and Famotidine. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Permax?

Permax has active ingredients of pergolide mesylate. eHealthMe is studying from 1,532 Permax users. Check the latest studies of Permax.

What is Famotidine?

Famotidine has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 83,421 Famotidine users. Check the latest studies of Famotidine.

On Jul, 03, 2026

33 people who take Permax and Famotidine together, and have interactions are studied.

Permax and Famotidine drug interactions.

What are the common drug interactions of Permax and Famotidine, by gender? *:

female:

Coma (state of unconsciousness lasting more than six hours)
Depressed level of consciousness
Fall
Haemoglobin decreased
Hypotonia (low muscle tone)
Miosis (constriction of the pupil of the eye, resulting from a normal response to an increase in light)
Urinary retention (the inability to completely or partially empty the bladder)
Adult respiratory distress syndrome (type of lung (pulmonary) failure)
Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
Atrioventricular block complete (heart block complete)

male:

Aortic valve incompetence
Pneumonia
Hallucination, visual (seeing things that aren't there)
Nail tinea (fungal infection of nail)
Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Restlessness (not able to rest)
Vomiting
Blood bilirubin increased
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)

What are the common drug interactions of Permax and Famotidine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Aortic valve incompetence
Difficulty in walking
Leukopenia (less number of white blood cells in blood)
Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Vomiting
Anaemia (lack of blood)
Constipation

What are the existing conditions these people have? *

Parkinson's Disease: 17 people, 51.52%
Osteoporosis (bones weak and more likely to break): 3 people, 9.09%
Insomnia (sleeplessness): 2 people, 6.06%
Atherosclerosis Obliterans (disorder of medium and large arteries of the lower extremity): 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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