Permax and Ketoprofen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Permax (pergolide mesylate) and Ketoprofen (ketoprofen). Common drug interactions include interstitial lung disease among females and femoral neck fracture among males.

The phase IV clinical study analyzes what interactions people have when they take Permax and Ketoprofen. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Permax?

Permax has active ingredients of pergolide mesylate. eHealthMe is studying from 1,532 Permax users. Check the latest studies of Permax.

What is Ketoprofen?

Ketoprofen has active ingredients of ketoprofen. It is often used in pain. eHealthMe is studying from 15,048 Ketoprofen users. Check the latest studies of Ketoprofen.



On Jul, 25, 2026

12 people who take Permax and Ketoprofen together, and have interactions are studied.

Permax and Ketoprofen drug interactions.

What are the common drug interactions of Permax and Ketoprofen, by gender? *:

female:

  1. Interstitial lung disease
  2. Acanthoma (a skin cancer)
  3. Atrioventricular block complete (heart block complete)
  4. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  5. Hyperkeratosis (thickening of the outer layer of the skin)
  6. Lobar pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung)
  7. Mitral valve incompetence (inefficient heart valve)
  8. Mitral valve stenosis (narrowing of mitral valve)
  9. Pericardial effusion (fluid around the heart)
  10. Pleurisy (inflammation of the pleurae, which causes pain when breathing)

male:

  1. Femoral neck fracture (neck of femur bone fracture)
  2. Sudden death
  3. Ulna fracture (fracture inside bone)
  4. Atrioventricular block first degree (heart block first degree)
  5. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  6. Cardiomegaly (increased size of heart than normal)
  7. Ventricular hypertrophy (enlargement of ventricles (lower chambers) in the heart)
  8. Arrhythmia (irregular heartbeat)
  9. Cardiac arrest
  10. Thrombosis (formation of a blood clot inside a blood vessel)

What are the common drug interactions of Permax and Ketoprofen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Acanthoma (a skin cancer)
  2. Atrioventricular block complete (heart block complete)
  3. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  4. Hyperkeratosis (thickening of the outer layer of the skin)
  5. Interstitial lung disease
  6. Lobar pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung)
  7. Mitral valve incompetence (inefficient heart valve)
  8. Mitral valve stenosis (narrowing of mitral valve)
  9. Pericardial effusion (fluid around the heart)
  10. Pleurisy (inflammation of the pleurae, which causes pain when breathing)

50-59:

n/a

60+:

  1. Femoral neck fracture (neck of femur bone fracture)
  2. Sudden death
  3. Lymphocyte stimulation test positive
  4. Pleural calcification (thickening of membranes around the lung a lung disease)
  5. Pleural effusion (water on the lungs)
  6. Pneumocystis jiroveci pneumonia (fungal infection of the lungs)
  7. Pneumonia cytomegaloviral (cmv pneumonia is caused by a member of a group of herpes-type viruses)
  8. Pneumonia primary atypical (primary atypical pneumonia which were probably caused by mycoplasma pneumoniae)
  9. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  10. Ventricular hypertrophy (enlargement of ventricles (lower chambers) in the heart)

What are the existing conditions these people have? *

  1. Parkinson's Disease: 8 people, 66.67%
  2. Restless Leg Syndrome (a powerful urge to move your legs): 3 people, 25.00%
  3. Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Permax and Ketoprofen?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Permax and Ketoprofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Permax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ketoprofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Permax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ketoprofen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on pergolide mesylate and ketoprofen (the active ingredients of Permax and Ketoprofen, respectively), and Permax and Ketoprofen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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