Perphenazine and Geodon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Perphenazine (perphenazine) and Geodon (ziprasidone hydrochloride). Common drug interactions include dizziness among females and type 2 diabetes mellitus among males.

The phase IV clinical study analyzes what interactions people have when they take Perphenazine and Geodon. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Perphenazine?

Perphenazine has active ingredients of perphenazine. It is often used in bipolar i disorder. eHealthMe is studying from 2,712 Perphenazine users. Check the latest studies of Perphenazine.

What is Geodon?

Geodon has active ingredients of ziprasidone hydrochloride. It is often used in bipolar disorder. eHealthMe is studying from 19,505 Geodon users. Check the latest studies of Geodon.

On Aug, 05, 2026

39 people who take Perphenazine and Geodon together, and have interactions are studied.

Perphenazine and Geodon drug interactions.

What are the common drug interactions of Perphenazine and Geodon, by gender? *:

female:

Dizziness
Drug effect decreased
Drug hypersensitivity
Drug level above therapeutic
Dry mouth
Ear pain
Emotional distress
Epstein-barr virus antibody positive
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Fibromyalgia (a long-term condition which causes pain all over the body)

male:

Type 2 diabetes mellitus
Pancreatitis (inflammation of pancreas)
Disturbance in attention
Dizziness
Fall
Judgement impaired
Liver injury
Visual impairment
Weight increased
Overdose

What are the common drug interactions of Perphenazine and Geodon, by age (0-1 to 60+)? *:

0-1:

Blood cholesterol increased
Blood triglycerides increased
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hyperlipidaemia (presence of excess lipids in the blood)
Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Ovarian cyst (fluid filled sac of the ovary)

2-9:

n/a

10-19:

n/a

20-29:

Stress
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic coma
Pancreatitis acute (sudden inflammation of pancreas)
Pancreatitis (inflammation of pancreas)
Anxiety
Blood cholesterol increased
Blood triglycerides increased
Constipation
Disturbance in attention

30-39:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Blood cholesterol increased
Blood triglycerides increased
Diabetic nephropathy (diabetic kidney disease)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Hyperlipidaemia (presence of excess lipids in the blood)
Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Ovarian cyst (fluid filled sac of the ovary)
Arthralgia (joint pain)
Asthenia (weakness)

40-49:

Type 2 diabetes mellitus
Drug ineffective
Overdose
Suicide attempt
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Alanine aminotransferase increased
Blood cholesterol increased
Blood creatine phosphokinase increased
Blood creatine phosphokinase mb increased
Blood glucose increased

50-59:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Type 2 diabetes mellitus
Arthralgia (joint pain)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Lymphatic disorder (disease of lymphatic system)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Myalgia (muscle pain)
Pain in extremity
Schizoaffective disorder (a mental disorder characterized by disordered thought)
Tardive dyskinesia (a disorder that involves involuntary movements)

60+:

Confusional state
Dizziness
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic gastroparesis (paralysis of the muscles of the stomach caused by diabetes)
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Glycosylated haemoglobin increased
Microalbuminuria (albumin into the urine)
Parkinsonism (degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination)
Tongue disorder (disease of tongue)
Type 2 diabetes mellitus

What are the existing conditions these people have? *

Depression: 13 people, 33.33%
Stress And Anxiety: 8 people, 20.51%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 6 people, 15.38%
Pain: 5 people, 12.82%
High Blood Cholesterol: 4 people, 10.26%
Insomnia (sleeplessness): 4 people, 10.26%
Itching: 4 people, 10.26%
Migraine (headache): 3 people, 7.69%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 7.69%
Inflammation: 3 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Perphenazine and Geodon?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously