Phenazopyridine hcl and Oxycodone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Phenazopyridine hcl (phenazopyridine hydrochloride) and Oxycodone (oxycodone hydrochloride). Common drug interactions include arthralgia among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Phenazopyridine hcl and Oxycodone. It is created by eHealthMe based on reports of 87 people who take the same drugs from the FDA, and is updated regularly.

What is Phenazopyridine hcl?

Phenazopyridine hcl has active ingredients of phenazopyridine hydrochloride. It is often used in urinary tract infection. eHealthMe is studying from 1,588 Phenazopyridine hcl users. Check the latest studies of Phenazopyridine hcl.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.

On Jul, 24, 2026

87 people who take Phenazopyridine hcl and Oxycodone together, and have interactions are studied.

Phenazopyridine hcl and Oxycodone drug interactions.

What are the common drug interactions of Phenazopyridine Hcl and Oxycodone, by gender? *:

female:

Arthralgia (joint pain)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Respiratory failure (inadequate gas exchange by the respiratory system)
Anxiety
Hypertension (high blood pressure)
Injury
Oropharyngeal pain
Septic shock (shock due to blood infection)
Abdominal pain
Decreased appetite

male:

Arthralgia (joint pain)
Abdominal pain
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone erosion
Cellulitis (infection under the skin)
Dental caries
Depression
Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)

What are the common drug interactions of Phenazopyridine Hcl and Oxycodone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Blood glucose increased
Blood pressure systolic decreased
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Heart rate increased
Unresponsive to stimuli
Ventricular fibrillation (abnormally irregular heart rhythm)
Abdominal pain upper
Cholecystitis chronic (long lasting infection of gallbladder)

20-29:

Adnexa uteri mass (ovarian cysts)
Arthralgia (joint pain)
Chest discomfort
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Dyspnoea (difficult or laboured respiration)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Hepatic steatosis (fatty liver disease)
Histoplasmosis (infection caused by breathing in spores of a fungus)
Hodgkin's disease (cancer originating from white blood cells)

30-39:

Abdominal pain
Abdominal hernia
Appendicitis perforated (perforated appendicitis is a condition in which an inflamed appendix bursts)
Arthralgia (joint pain)
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Diarrhoea
Dysphagia (a condition in which swallowing is difficult or painful)
Hodgkin's disease (cancer originating from white blood cells)
Injury
Intervertebral disc degeneration (spinal disc degeneration)

40-49:

Drug ineffective
Liver injury
Portal vein thrombosis (venous thrombosis affecting the hepatic portal vein)
Spleen disorder (disease of spleen)
Tremor (trembling or shaking movements in one or more parts of your body)
Affect lability (emotional incontinence)
Agoraphobia (extreme or irrational fear of crowded spaces or enclosed public places)
Asthenia (weakness)
Blood pressure increased
Crying

50-59:

Intervertebral disc protrusion (spinal disc protrusion)
Muscular weakness (muscle weakness)
Nausea (feeling of having an urge to vomit)
Pain in jaw
Pyrexia (fever)
Trigeminal neuralgia (a painful condition of the nerve responsible for most facial sensation)
Abasia (inability to walk)
Abdominal pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Bedridden

60+:

Dysphagia (a condition in which swallowing is difficult or painful)
Arthralgia (joint pain)
Nausea (feeling of having an urge to vomit)
Hyperaesthesia
Pneumonia
Anaemia (lack of blood)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bradycardia (abnormally slow heart action)
Cellulitis (infection under the skin)
Dehydration (dryness resulting from the removal of water)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 11 people, 12.64%
Metastases To Bone (cancer spreads to bone): 10 people, 11.49%
Sleep Disorder: 8 people, 9.20%
Neoplasm Malignant (cancer tumour): 7 people, 8.05%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 7 people, 8.05%
Depression: 7 people, 8.05%
Fibromyalgia (a long-term condition which causes pain all over the body): 6 people, 6.90%
Cystitis Interstitial (unknown cause characterized by bladder pain): 6 people, 6.90%
Cough: 6 people, 6.90%
Cardiac Disorder: 6 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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