Phenergan and Myfortic drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Phenergan (promethazine hydrochloride) and Myfortic (mycophenolic acid). Common drug interactions include dyspepsia among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Phenergan and Myfortic. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Phenergan?

Phenergan has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 25,312 Phenergan users. Check the latest studies of Phenergan.

What is Myfortic?

Myfortic has active ingredients of mycophenolic acid. It is often used in kidney transplant. eHealthMe is studying from 13,331 Myfortic users. Check the latest studies of Myfortic.



On Aug, 02, 2026

31 people who take Phenergan and Myfortic together, and have interactions are studied.

Phenergan and Myfortic drug interactions.

What are the common drug interactions of Phenergan and Myfortic, by gender? *:

female:

  1. Dyspepsia (indigestion)
  2. Electrolyte imbalance
  3. Irritable bowel syndrome
  4. Liver disorder (liver diseases)
  5. Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract)
  6. Viral infection
  7. Blood disorder
  8. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  9. Chronic kidney disease
  10. Cold sweat

male:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Hypotension (abnormally low blood pressure)
  4. Impaired gastric emptying
  5. Implant site infection
  6. Lethargy (tiredness)
  7. Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
  8. Septic shock (shock due to blood infection)
  9. Nephrogenic anaemia (anaemia due to kidney disease)
  10. Renal injury (kidney injury)

What are the common drug interactions of Phenergan and Myfortic, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Liver disorder (liver diseases)
  2. Chest pain
  3. Chronic kidney disease
  4. Epistaxis (bleed from the nose)
  5. Haematemesis (vomiting of blood)
  6. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  7. Nephrogenic anaemia (anaemia due to kidney disease)
  8. Pseudomonal bacteraemia (p. aeruginosa cause of bacterial infections of the blood)
  9. Pyelonephritis (inflammation of kidney caused by bacteria)
  10. Pyrexia (fever)

30-39:

  1. Acidosis (build-up of carbon dioxide in the blood)
  2. Dehydration (dryness resulting from the removal of water)
  3. Diarrhoea
  4. Gastroenteritis (inflammation of stomach and intestine)
  5. Haemoglobin decreased
  6. Headache (pain in head)
  7. Muscle disorder (muscle disease)
  8. Muscle spasms (muscle contraction)
  9. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  10. Renal impairment (severely reduced kidney function)

40-49:

  1. Pulmonary embolism (blockage of the main artery of the lung)
  2. Renal failure (kidney dysfunction)
  3. Abdominal pain
  4. Diarrhoea
  5. Immunosuppressant drug level increased
  6. Abdominal distension
  7. Anaemia (lack of blood)
  8. Back pain
  9. Blood folate decreased
  10. Blood urea increased

50-59:

  1. Blood creatinine increased
  2. Abdominal pain
  3. Alanine aminotransferase decreased
  4. Cardiorenal syndrome (kidney failure and heart failure)
  5. Cellulitis (infection under the skin)
  6. Chronic kidney disease
  7. Hypervolaemia (abnormally increased volume of blood)
  8. Hypoglycaemia (deficiency of glucose in the bloodstream)
  9. Hypotension (abnormally low blood pressure)
  10. Impaired gastric emptying

60+:

  1. Syncope (loss of consciousness with an inability to maintain postural tone)
  2. Renal failure acute (rapid kidney dysfunction)
  3. Fluid overload (too much fluid in the blood)
  4. Generalised oedema (swelling all over the body)
  5. Hypertension (high blood pressure)
  6. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  7. Iron deficiency
  8. Left ventricular failure (left ventricle fails to contract forcefully)
  9. Lung consolidation (a condition whereby the lung tissues solidify because of the accumulation of solid and liquid material in the air spaces)
  10. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)

What are the existing conditions these people have? *

  1. High Blood Pressure: 7 people, 22.58%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 19.35%
  3. Hepatitis C: 5 people, 16.13%
  4. Stress And Anxiety: 4 people, 12.90%
  5. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 12.90%
  6. Pain: 4 people, 12.90%
  7. Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 4 people, 12.90%
  8. Sleep Disorder: 3 people, 9.68%
  9. Indigestion: 3 people, 9.68%
  10. Depression: 3 people, 9.68%

* Approximation only. Some reports may have incomplete information.

Do you take Phenergan and Myfortic?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Phenergan and Myfortic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Phenergan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Myfortic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Phenergan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Myfortic and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on promethazine hydrochloride and mycophenolic acid (the active ingredients of Phenergan and Myfortic, respectively), and Phenergan and Myfortic (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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