Phenergan and Vascepa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Phenergan (promethazine hydrochloride) and Vascepa (icosapent ethyl). Common drug interactions include arthralgia among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Phenergan and Vascepa. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Phenergan?

Phenergan has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 25,312 Phenergan users. Check the latest studies of Phenergan.

What is Vascepa?

Vascepa has active ingredients of icosapent ethyl. It is often used in high blood cholesterol. eHealthMe is studying from 5,894 Vascepa users. Check the latest studies of Vascepa.

On Jul, 08, 2026

22 people who take Phenergan and Vascepa together, and have interactions are studied.

Phenergan and Vascepa drug interactions.

What are the common drug interactions of Phenergan and Vascepa, by gender? *:

female:

Arthralgia (joint pain)
Dysstasia (difficulty in standing)
Fatigue (feeling of tiredness)
Gait disturbance
Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Blood magnesium decreased
Decreased activity
Emotional distress

male:

Renal failure (kidney dysfunction)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Pain
Renal impairment (severely reduced kidney function)
Renal transplant
Tooth loss
Decreased activity
Impaired work ability
Nephrogenic anaemia (anaemia due to kidney disease)
Arthralgia (joint pain)

What are the common drug interactions of Phenergan and Vascepa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Hospitalisation

40-49:

Renal failure (kidney dysfunction)
Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Decreased activity
Impaired work ability
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hyperkalaemia (damage to or disease of the kidney)

50-59:

Arthralgia (joint pain)
Dysstasia (difficulty in standing)
Gait disturbance
Pelvic pain

60+:

Blood magnesium decreased
Haemoglobin decreased
Platelet count decreased
Renal impairment (severely reduced kidney function)
Arthralgia (joint pain)
Myalgia (muscle pain)

What are the existing conditions these people have? *

Hiv Infection: 7 people, 31.82%
High Blood Pressure: 5 people, 22.73%
Diabetes: 5 people, 22.73%
Procedural Pain: 4 people, 18.18%
Malignant Peritoneal Neoplasm (cancer tumour of peritoneum): 4 people, 18.18%
Infection: 4 people, 18.18%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 13.64%
Ill-Defined Disorder: 2 people, 9.09%
Drowsiness: 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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