Phentermine and Azithromycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Phentermine (phentermine hydrochloride) and Azithromycin (azithromycin). Common drug interactions include dependence among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Phentermine and Azithromycin. It is created by eHealthMe based on reports of 90 people who take the same drugs from the FDA, and is updated regularly.

What is Phentermine?

Phentermine has active ingredients of phentermine hydrochloride. It is often used in weight loss. eHealthMe is studying from 19,870 Phentermine users. Check the latest studies of Phentermine.

What is Azithromycin?

Azithromycin has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 40,716 Azithromycin users. Check the latest studies of Azithromycin.

On Jul, 14, 2026

90 people who take Phentermine and Azithromycin together, and have interactions are studied.

Phentermine and Azithromycin drug interactions.

What are the common drug interactions of Phentermine and Azithromycin, by gender? *:

female:

Dependence
Diarrhoea
Disability
Drug abuse
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Eating disorder
Emotional distress
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Fibromyalgia (a long-term condition which causes pain all over the body)
Groin infection (infection in groin)

male:

Chronic kidney disease
Emotional distress
Poor peripheral circulation
Subclavian artery thrombosis (a condition in which the blood flow through the vessel is obstructed)
Craniosynostosis (a baby is born with an abnormally shaped skull or develops one during growth)
Osteoporosis (bones weak and more likely to break)
Arterial thrombosis (formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system)
Cardiac failure
Neuropathy peripheral (surface nerve damage)
Pneumonia

What are the common drug interactions of Phentermine and Azithromycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Asthenia (weakness)
Disturbance in attention
Dizziness
Fatigue (feeling of tiredness)
Head discomfort
Hypoaesthesia (reduced sense of touch or sensation)
Mood altered (changes in mood)
Palpitations (feelings or sensations that your heart is pounding or racing)
Somnolence (a state of near-sleep, a strong desire for sleep)

20-29:

Anxiety
Groin infection (infection in groin)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Sepsis (a severe blood infection that can lead to organ failure and death)
Soft tissue infection
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Injury
Pain
Anal abscess
Depression

30-39:

Fall
Insomnia (sleeplessness)
Nervousness
Syncope (loss of consciousness with an inability to maintain postural tone)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pain
Pulmonary embolism (blockage of the main artery of the lung)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Chronic fatigue syndrome (disorder that causes extreme fatigue)
Dehydration (dryness resulting from the removal of water)

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Nephrogenic anaemia (anaemia due to kidney disease)
Abscess (pus)
Abscess limb (limb infection)
Anal abscess
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased

50-59:

Iga nephropathy (kidney disease- condition prevents the kidneys from filtering waste)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Nephrogenic anaemia (anaemia due to kidney disease)
Osteoporosis (bones weak and more likely to break)
Proteinuria (presence of protein in the urine)
Renal tubular necrosis (death of kidney tubules)
Weight decreased
Anaemia (lack of blood)
Depression
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)

60+:

Anxiety
Chronic kidney disease
Subclavian artery thrombosis (a condition in which the blood flow through the vessel is obstructed)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Arterial thrombosis (formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system)
Cardiac failure
Drug ineffective
Neuropathy peripheral (surface nerve damage)
Osteopenia (a condition where bone mineral density is lower than normal)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 26 people, 28.89%
Pain: 23 people, 25.56%
Depression: 21 people, 23.33%
High Blood Pressure: 18 people, 20.00%
Weight Decreased: 16 people, 17.78%
High Blood Cholesterol: 16 people, 17.78%
Stress And Anxiety: 15 people, 16.67%
Infection: 15 people, 16.67%
Migraine (headache): 11 people, 12.22%
Insomnia (sleeplessness): 11 people, 12.22%

* Approximation only. Some reports may have incomplete information.

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