Phentermine and Botox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Phentermine (phentermine hydrochloride) and Botox (botulinum toxin type a). Common drug interactions include nausea among females.

The phase IV clinical study analyzes what interactions people have when they take Phentermine and Botox. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Phentermine?

Phentermine has active ingredients of phentermine hydrochloride. It is often used in weight loss. eHealthMe is studying from 19,870 Phentermine users. Check the latest studies of Phentermine.

What is Botox?

Botox has active ingredients of botulinum toxin type a. It is often used in migraine. eHealthMe is studying from 70,513 Botox users. Check the latest studies of Botox.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 30, 2026

39 people who take Phentermine and Botox together, and have interactions are studied.

Phentermine and Botox drug interactions.

What are the common drug interactions of Phentermine and Botox, by gender? *:

female:

  1. Nausea (feeling of having an urge to vomit)
  2. Drug ineffective
  3. Surgery
  4. Urinary tract infection
  5. Abdominal pain upper
  6. Anxiety
  7. Concussion (short loss of normal brain function in response to a head injury)
  8. Dysphagia (a condition in which swallowing is difficult or painful)
  9. Feeling drunk
  10. Hypoaesthesia (reduced sense of touch or sensation)

male:

n/a

What are the common drug interactions of Phentermine and Botox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Injection site bruising
  2. Trigeminal neuralgia (a painful condition of the nerve responsible for most facial sensation)

30-39:

  1. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
  2. Dry skin
  3. Dysphagia (a condition in which swallowing is difficult or painful)
  4. Hypoaesthesia (reduced sense of touch or sensation)
  5. Injection site haemorrhage (bleeding from injection site)
  6. Lipase decreased
  7. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  8. Muscular weakness (muscle weakness)
  9. Nasal oedema (fluid collection in nose)
  10. Pain

40-49:

  1. Drug ineffective
  2. Depression
  3. Insomnia (sleeplessness)
  4. Abdominal pain upper
  5. Concussion (short loss of normal brain function in response to a head injury)
  6. Feeling drunk
  7. Nausea (feeling of having an urge to vomit)
  8. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  9. Vitamin d deficiency
  10. Vomiting

50-59:

  1. Alopecia (absence of hair from areas of the body)
  2. Amaurosis fugax (painless transient monocular visual loss)
  3. Anxiety
  4. Blood albumin decreased
  5. Blood potassium decreased
  6. Burning sensation
  7. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  8. Chest pain
  9. Chills (felling of cold)
  10. Chronic kidney disease

60+:

  1. Muscle mass
  2. Myalgia (muscle pain)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 25.64%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 8 people, 20.51%
  3. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 20.51%
  4. Pain: 6 people, 15.38%
  5. Nausea (feeling of having an urge to vomit): 6 people, 15.38%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 12.82%
  7. Skin Wrinkling (wrinkle on skin): 5 people, 12.82%
  8. Muscle Spasms (muscle contraction): 5 people, 12.82%
  9. Weight Decreased: 4 people, 10.26%
  10. Asthma: 4 people, 10.26%

* Approximation only. Some reports may have incomplete information.

Do you take Phentermine and Botox?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Phentermine and Botox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Phentermine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Botox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Phentermine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Botox and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on phentermine hydrochloride and botulinum toxin type a (the active ingredients of Phentermine and Botox, respectively), and Phentermine and Botox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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