Phentermine and Cetirizine hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Phentermine (phentermine hydrochloride) and Cetirizine hydrochloride (cetirizine hydrochloride). Common drug interactions include headache among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Phentermine and Cetirizine hydrochloride. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Phentermine?

Phentermine has active ingredients of phentermine hydrochloride. It is often used in weight loss. eHealthMe is studying from 19,870 Phentermine users. Check the latest studies of Phentermine.

What is Cetirizine hydrochloride?

Cetirizine hydrochloride has active ingredients of cetirizine hydrochloride. It is often used in allergies. eHealthMe is studying from 34,908 Cetirizine hydrochloride users. Check the latest studies of Cetirizine hydrochloride.



On Jul, 13, 2026

26 people who take Phentermine and Cetirizine hydrochloride together, and have interactions are studied.

Phentermine and Cetirizine hydrochloride drug interactions.

What are the common drug interactions of Phentermine and Cetirizine Hydrochloride, by gender? *:

female:

  1. Headache (pain in head)
  2. Abdominal discomfort
  3. Arthralgia (joint pain)
  4. Back disorder
  5. Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
  6. Sinusitis (inflammation of sinus)
  7. Chronic kidney disease
  8. Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
  9. Sinus congestion (blockage of sinus)
  10. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

male:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Osteoporosis (bones weak and more likely to break)
  4. Pain
  5. Quality of life decreased
  6. Spinal compression fracture (fracture due to spinal compression on bone)
  7. Weight increased
  8. Decreased activity
  9. Drug ineffective
  10. Emotional distress

What are the common drug interactions of Phentermine and Cetirizine Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Cardiac flutter (abnormal heart rhythm)
  2. Hyperhidrosis (abnormally increased sweating)
  3. Gallbladder operation

30-39:

  1. Asthma
  2. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  3. Drug ineffective
  4. Oropharyngeal pain

40-49:

  1. Arthralgia (joint pain)
  2. Dry mouth
  3. Gait disturbance
  4. Lip dry
  5. Pruritus (severe itching of the skin)
  6. Therapeutic response unexpected

50-59:

  1. Chronic kidney disease
  2. Arthralgia (joint pain)
  3. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  4. Impaired gastric emptying
  5. Renal failure (kidney dysfunction)
  6. Asthenia (weakness)
  7. Back pain
  8. Bone pain
  9. Chest discomfort
  10. Dyspnoea (difficult or laboured respiration)

60+:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Quality of life decreased
  4. Spinal compression fracture (fracture due to spinal compression on bone)
  5. Weight increased
  6. Decreased activity
  7. Emotional distress
  8. Fracture
  9. Kyphosis (a condition of over-curvature of the thoracic vertebrae (upper back))
  10. Mobility decreased (ability to move is reduced)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 19.23%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 15.38%
  3. Immunodeficiency Common Variable: 4 people, 15.38%
  4. Hypersensitivity: 3 people, 11.54%
  5. Multiple Allergies (allergy to multiple agents): 3 people, 11.54%
  6. Pain: 3 people, 11.54%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 11.54%
  8. High Blood Pressure: 3 people, 11.54%
  9. High Blood Cholesterol: 2 people, 7.69%
  10. Asthma: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Phentermine and Cetirizine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Phentermine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cetirizine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Phentermine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cetirizine hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on phentermine hydrochloride and cetirizine hydrochloride (the active ingredients of Phentermine and Cetirizine hydrochloride, respectively), and Phentermine and Cetirizine hydrochloride (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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