Phentermine and Daypro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Phentermine (phentermine hydrochloride) and Daypro (oxaprozin). Common drug interactions include pharyngitis among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Phentermine and Daypro. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Phentermine?

Phentermine has active ingredients of phentermine hydrochloride. It is often used in weight loss. eHealthMe is studying from 19,870 Phentermine users. Check the latest studies of Phentermine.

What is Daypro?

Daypro has active ingredients of oxaprozin. It is often used in osteoarthritis. eHealthMe is studying from 2,883 Daypro users. Check the latest studies of Daypro.



On Aug, 05, 2026

30 people who take Phentermine and Daypro together, and have interactions are studied.

Phentermine and Daypro drug interactions.

What are the common drug interactions of Phentermine and Daypro, by gender? *:

female:

  1. Pharyngitis (inflammation of the pharynx, causing a sore throat)
  2. Psychotic disorder
  3. Renal failure (kidney dysfunction)
  4. Renal impairment (severely reduced kidney function)
  5. Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
  6. Speech disorder
  7. Tricuspid valve disease (disease of heart valve)
  8. Weight decreased
  9. Word salad
  10. Chest pain

male:

  1. Dyspnoea (difficult or laboured respiration)
  2. Alopecia (absence of hair from areas of the body)
  3. Depression
  4. Drug maladministration
  5. Feeling jittery
  6. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  7. Headache (pain in head)
  8. Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
  9. Oedema lower limb (fluid collection in tissue of lower leg)
  10. Orthopnoea (shortness of breath (dyspnea) when lying down)

What are the common drug interactions of Phentermine and Daypro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Chest pain
  2. Dyspnoea (difficult or laboured respiration)
  3. Abortion early (terminate pregnancy during its earliest stages, between 5 and 10 weeks)
  4. Depression
  5. Device dislocation
  6. Drug ineffective
  7. Emotional distress
  8. Injury

30-39:

  1. Cardiovascular disorder (heart diseases)
  2. Confusion
  3. Insomnia (sleeplessness)
  4. Irritability
  5. Thinking abnormal
  6. Asthma
  7. Chest pain
  8. Cough
  9. Crying
  10. Depression

40-49:

  1. Chest pain
  2. Dyspnoea (difficult or laboured respiration)
  3. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  4. Alopecia (absence of hair from areas of the body)
  5. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  6. Anxiety
  7. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  8. Blood pressure increased
  9. Cardiomegaly (increased size of heart than normal)
  10. Cardiovascular disorder (heart diseases)

50-59:

  1. Alopecia (absence of hair from areas of the body)
  2. Angina pectoris (chest pain due to ischemia of the heart muscle)
  3. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  4. Cardiac murmur (an heart sound in valve abnormality)
  5. Chronic kidney disease
  6. Diarrhoea
  7. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  8. Nephrogenic anaemia (anaemia due to kidney disease)
  9. Nephropathy (damage to or disease of a kidney)
  10. Renal failure (kidney dysfunction)

60+:

  1. Chronic kidney disease
  2. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  3. Renal injury (kidney injury)
  4. Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 10.00%
  2. Infection: 3 people, 10.00%
  3. High Blood Pressure: 3 people, 10.00%
  4. Diabetes: 3 people, 10.00%
  5. Diarrhea: 2 people, 6.67%
  6. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 2 people, 6.67%
  7. Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 6.67%
  8. Cardiac Failure Congestive: 2 people, 6.67%
  9. Constipation: 2 people, 6.67%
  10. Cough: 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Phentermine and Daypro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Phentermine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Daypro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Phentermine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Daypro and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on phentermine hydrochloride and oxaprozin (the active ingredients of Phentermine and Daypro, respectively), and Phentermine and Daypro (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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