Phentermine and Glucotrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Phentermine (phentermine hydrochloride) and Glucotrol (glipizide). Common drug interactions include respiratory distress among females and angina pectoris among males.

The phase IV clinical study analyzes what interactions people have when they take Phentermine and Glucotrol. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Phentermine?

Phentermine has active ingredients of phentermine hydrochloride. It is often used in weight loss. eHealthMe is studying from 19,870 Phentermine users. Check the latest studies of Phentermine.

What is Glucotrol?

Glucotrol has active ingredients of glipizide. It is often used in diabetes. eHealthMe is studying from 20,322 Glucotrol users. Check the latest studies of Glucotrol.

On Jul, 11, 2026

25 people who take Phentermine and Glucotrol together, and have interactions are studied.

Phentermine and Glucotrol drug interactions.

What are the common drug interactions of Phentermine and Glucotrol, by gender? *:

female:

Respiratory distress (difficulty in breathing)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Small intestinal obstruction (blockage in small intestine)
Tendonitis (a condition that causes pain and swelling of tendons)
Vision blurred
Agitation (state of anxiety or nervous excitement)
Alopecia (absence of hair from areas of the body)
Atherosclerosis (disorder of the arteries)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)

male:

Angina pectoris (chest pain due to ischemia of the heart muscle)
Headache (pain in head)
Arthralgia (joint pain)
Balance disorder
Bradycardia (abnormally slow heart action)
Cardiac murmur (an heart sound in valve abnormality)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cardiomegaly (increased size of heart than normal)
Cardiovascular disorder (heart diseases)
Cerebral haematoma (collection of blood in brain)

What are the common drug interactions of Phentermine and Glucotrol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Arthralgia (joint pain)
Blood cholesterol increased
Cardiovascular disorder (heart diseases)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Depression
Diabetes mellitus inadequate control
Essential hypertension (primary hypertension)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Migraine with aura (headache with vision weakness)
Muscle spasms (muscle contraction)

50-59:

Insomnia (sleeplessness)
Pain in limb
Palpitations (feelings or sensations that your heart is pounding or racing)
Pulmonary embolism (blockage of the main artery of the lung)
Thrombosis (formation of a blood clot inside a blood vessel)
Dyspnoea (difficult or laboured respiration)
Nervousness
Cardiac failure
Cardiovascular disorder (heart diseases)
Oedema peripheral (superficial swelling)

60+:

Valvular heart disease (diseases of the heart valves)
Chest pain
Angina pectoris (chest pain due to ischemia of the heart muscle)
Anxiety
Atherosclerosis (disorder of the arteries)
Balance disorder
Bradycardia (abnormally slow heart action)
Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)
Calcinosis (calcium deposits in any soft tissue)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)

What are the existing conditions these people have? *

Pain: 4 people, 16.00%
Wheezing (a high-pitched whistling sound made while you breath): 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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