Phentermine and Oxycodone hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Phentermine (phentermine hydrochloride) and Oxycodone hydrochloride (oxycodone hydrochloride). Common drug interactions include blood potassium decreased among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Phentermine and Oxycodone hydrochloride. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Phentermine?

Phentermine has active ingredients of phentermine hydrochloride. It is often used in weight loss. eHealthMe is studying from 19,870 Phentermine users. Check the latest studies of Phentermine.

What is Oxycodone hydrochloride?

Oxycodone hydrochloride has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 36,817 Oxycodone hydrochloride users. Check the latest studies of Oxycodone hydrochloride.

On Jul, 26, 2026

16 people who take Phentermine and Oxycodone hydrochloride together, and have interactions are studied.

Phentermine and Oxycodone hydrochloride drug interactions.

What are the common drug interactions of Phentermine and Oxycodone Hydrochloride, by gender? *:

female:

Blood potassium decreased
Post procedural infection
Surgery
Completed suicide (act of taking one's own life)
Headache (pain in head)
Oedema peripheral (superficial swelling)
Alcohol abuse
Anxiety
Chronic kidney disease
Drug dependence

male:

Diarrhoea
Arrhythmia (irregular heartbeat)
Hallucination (an experience involving the perception of something not present)
Hospitalisation
Hyperhidrosis (abnormally increased sweating)
Impaired reasoning
Impaired work ability
Inguinal hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)
Joint instability (a condition in which the joints aren't sufficiently supported)
Limb injury

What are the common drug interactions of Phentermine and Oxycodone Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Alcohol abuse
Anxiety
Drug dependence
Overdose
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

30-39:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Renal tubular necrosis (death of kidney tubules)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Parosmia (distortion of the sense of smell, as in smelling odours that are not present)

40-49:

Cardiac arrest
Completed suicide (act of taking one's own life)
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)

50-59:

Asthenia (weakness)
Pain in extremity
Swelling face
Vision blurred
Completed suicide (act of taking one's own life)
Gait disturbance
Hyperaesthesia
Joint swelling
Local swelling (swelling at the site of some application of substance or injury)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

60+:

Eye pain

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 25.00%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 25.00%
Immunodeficiency Common Variable: 2 people, 12.50%
Drowsiness: 2 people, 12.50%
High Blood Pressure: 1 person, 6.25%
Back Injury: 1 person, 6.25%
Back Pain: 1 person, 6.25%
Brain Neoplasm Malignant (brain cancer tumour): 1 person, 6.25%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.25%
Weight Decreased: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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