Phoslo and Alphagan drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Phoslo (calcium acetate) and Alphagan (brimonidine tartrate). Common drug interactions include abdominal pain among females and abdominal pain among males.
The phase IV clinical study analyzes what interactions people have when they take Phoslo and Alphagan. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.
What is Phoslo?
Phoslo has active ingredients of calcium acetate. eHealthMe is studying from 4,291 Phoslo users. Check the latest studies of Phoslo.
What is Alphagan?
Alphagan has active ingredients of brimonidine tartrate. It is often used in glaucoma. eHealthMe is studying from 9,981 Alphagan users. Check the latest studies of Alphagan.
18 people who take Phoslo and Alphagan together, and have interactions are studied.

What are the common drug interactions of Phoslo and Alphagan, by gender? *:
female:
- Abdominal pain
- Abdominal pain upper
- Asthenia (weakness)
- Diarrhoea
- Discomfort
- Dizziness
- Dyspepsia (indigestion)
- Flushing (the warm, red condition of human skin)
- Heart rate increased
- Nausea (feeling of having an urge to vomit)
male:
- Abdominal pain
- Arteriosclerosis (thickening and hardening of arteries)
- Cardiomegaly (increased size of heart than normal)
- Eye inflammation
- Flushing (the warm, red condition of human skin)
- Haematochezia (passage of stools containing blood)
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
- Heart rate decreased
- Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
- Impaired gastric emptying
What are the common drug interactions of Phoslo and Alphagan, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Abdominal pain
- Abdominal pain upper
- Asthenia (weakness)
- Diarrhoea
- Discomfort
- Dizziness
- Dyspepsia (indigestion)
- Flushing (the warm, red condition of human skin)
- Heart rate increased
- Nausea (feeling of having an urge to vomit)
50-59:
- Cellulitis (infection under the skin)
- Flushing (the warm, red condition of human skin)
- Herpes zoster
- Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- White blood cell count decreased
- Abdominal pain
- Abdominal pain upper
- Asthenia (weakness)
- Blood glucose increased
60+:
- Abdominal pain
- Arteriosclerosis (thickening and hardening of arteries)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Haematochezia (passage of stools containing blood)
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
- Heart rate decreased
- Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
- Impaired gastric emptying
- Lactic acidosis (low ph in body tissues)
- Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
What are the existing conditions these people have? *
- High Blood Cholesterol: 3 people, 16.67%
- Headache (pain in head): 2 people, 11.11%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 11.11%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 11.11%
- Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 2 people, 11.11%
- Chronic Renal Failure (kidney failure): 2 people, 11.11%
- Cough: 2 people, 11.11%
- Diabetes: 2 people, 11.11%
- Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 11.11%
- Fungal Infection: 2 people, 11.11%
* Approximation only. Some reports may have incomplete information.
Do you take Phoslo and Alphagan?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Phoslo and Alphagan:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Phoslo:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Alphagan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Phoslo and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Alphagan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on calcium acetate and brimonidine tartrate (the active ingredients of Phoslo and Alphagan, respectively), and Phoslo and Alphagan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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