Phytonadione and Reglan drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Phytonadione (phytonadione) and Reglan (metoclopramide hydrochloride). Common drug interactions include multi-organ failure among females and dyspnoea among males.
The phase IV clinical study analyzes what interactions people have when they take Phytonadione and Reglan. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.
What is Phytonadione?
Phytonadione has active ingredients of phytonadione. It is often used in hemorrhagic stroke. eHealthMe is studying from 2,870 Phytonadione users. Check the latest studies of Phytonadione.
What is Reglan?
Reglan has active ingredients of metoclopramide hydrochloride. It is often used in gastroparesis. eHealthMe is studying from 29,455 Reglan users. Check the latest studies of Reglan.
52 people who take Phytonadione and Reglan together, and have interactions are studied.

What are the common drug interactions of Phytonadione and Reglan, by gender? *:
female:
- Multi-organ failure (multisystem organ failure)
- Diarrhoea
- Pleural effusion (water on the lungs)
- Anxiety
- Dyspnoea (difficult or laboured respiration)
- Renal failure chronic (long lasting kidney dysfunction)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Vomiting
- Atelectasis (partial or complete collapse of the lung)
- Cough
male:
- Dyspnoea (difficult or laboured respiration)
- Oedema peripheral (superficial swelling)
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
- Dyspepsia (indigestion)
- Lung nodule (solid, raised areas in lung)
- Night sweats (sweating in night)
- Pain
- Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
- Arrhythmia (irregular heartbeat)
- Fatigue (feeling of tiredness)
What are the common drug interactions of Phytonadione and Reglan, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Pancreatitis (inflammation of pancreas)
10-19:
- Acute lymphocytic leukaemia (cancer of the white blood cells)
- Agitation (state of anxiety or nervous excitement)
- Ammonia increased
- Apnoea (suspension of external breathing)
- Ascites (accumulation of fluid in the abdominal cavity)
- Atelectasis (partial or complete collapse of the lung)
- Chest discomfort
- Clonus (series of involuntary, rhythmic, muscular contractions and relaxations)
- Coagulopathy (blood's ability to clot is impaired)
- Confusional state
20-29:
n/a
30-39:
- Abdominal pain
- Abscess (pus)
- Acute respiratory distress syndrome
- Anxiety
- Atelectasis (partial or complete collapse of the lung)
- Bacterial sepsis
- Blood glucose increased
- Cardiac failure
- Cellulitis (infection under the skin)
- Cyst (a closed sac)
40-49:
- Abdominal discomfort
- Abdominal distension
- Acute respiratory distress syndrome
- Agitation (state of anxiety or nervous excitement)
- Anasarca (general swelling, or massive oedema)
- Anxiety
- Arrhythmia (irregular heartbeat)
- Ascites (accumulation of fluid in the abdominal cavity)
- Atelectasis (partial or complete collapse of the lung)
- Bacteraemia (presence of bacteria in the blood)
50-59:
- Drug dependence
- Dyspnoea (difficult or laboured respiration)
- Insomnia (sleeplessness)
- Malaise (a feeling of general discomfort or uneasiness)
- Nasopharyngitis (inflammation of the nasopharynx)
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Sinusitis (inflammation of sinus)
- Weight decreased
- Chest pain
- Colitis (inflammation of colon)
60+:
- Multi-organ failure (multisystem organ failure)
- Renal failure chronic (long lasting kidney dysfunction)
- Hypotension (abnormally low blood pressure)
- Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
- Urinary tract infection
- Ascites (accumulation of fluid in the abdominal cavity)
- Blood pressure decreased
- Blood pressure fluctuation
- Cardiac arrest
- Coma (state of unconsciousness lasting more than six hours)
What are the existing conditions these people have? *
- Pain: 10 people, 19.23%
- Multiple Myeloma (cancer of the plasma cells): 9 people, 17.31%
- Constipation: 5 people, 9.62%
- Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 5 people, 9.62%
- Pulmonary Embolism (blockage of the main artery of the lung): 3 people, 5.77%
- Agitation (state of anxiety or nervous excitement): 3 people, 5.77%
* Approximation only. Some reports may have incomplete information.
Do you take Phytonadione and Reglan?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Phytonadione (2,870 reports)
- Reglan (29,455 reports)
Browse all drug interactions of Phytonadione and Reglan:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Phytonadione:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Reglan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Phytonadione and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Reglan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on phytonadione and metoclopramide hydrochloride (the active ingredients of Phytonadione and Reglan, respectively), and Phytonadione and Reglan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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