Pifeltro and Dovato drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pifeltro (doravirine) and Dovato (dolutegravir sodium; lamivudine). Common drug interactions include rash among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Pifeltro and Dovato. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Pifeltro?

Pifeltro has active ingredients of doravirine. eHealthMe is studying from 476 Pifeltro users. Check the latest studies of Pifeltro.

What is Dovato?

Dovato has active ingredients of dolutegravir sodium; lamivudine. It is often used in hiv infection. eHealthMe is studying from 2,537 Dovato users. Check the latest studies of Dovato.



On Jul, 05, 2026

14 people who take Pifeltro and Dovato together, and have interactions are studied.

Pifeltro and Dovato drug interactions.

What are the common drug interactions of Pifeltro and Dovato, by gender? *:

female:

  1. Rash

male:

  1. Nausea (feeling of having an urge to vomit)
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Osteoporosis (bones weak and more likely to break)
  4. Pain in extremity
  5. Pain in jaw
  6. Renal failure (kidney dysfunction)
  7. Surgery
  8. Agitation (state of anxiety or nervous excitement)
  9. Ankle fracture
  10. Arthralgia (joint pain)

What are the common drug interactions of Pifeltro and Dovato, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Asthenia (weakness)
  4. Chronic kidney disease
  5. Decreased activity
  6. Emotional distress
  7. Fear
  8. Insomnia (sleeplessness)
  9. Pain
  10. Quality of life decreased

40-49:

n/a

50-59:

n/a

60+:

  1. Nausea (feeling of having an urge to vomit)
  2. Mobility decreased (ability to move is reduced)
  3. Pain
  4. Pain in extremity
  5. Pain in jaw
  6. Renal failure (kidney dysfunction)
  7. Agitation (state of anxiety or nervous excitement)
  8. Ankle fracture
  9. Arthralgia (joint pain)
  10. Blood creatinine increased

What are the existing conditions these people have? *

  1. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 21.43%
  2. Spinal Disorder (disease of spine a back bone): 1 person, 7.14%
  3. Limb Discomfort (discomfort in leg): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Pifeltro and Dovato?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Pifeltro and Dovato:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pifeltro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Dovato:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pifeltro and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dovato and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on doravirine and dolutegravir sodium; lamivudine (the active ingredients of Pifeltro and Dovato, respectively), and Pifeltro and Dovato (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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