Pioglitazone and Lenalidomide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pioglitazone (pioglitazone hydrochloride) and Lenalidomide (lenalidomide). Common drug interactions include anaemia among females and septic shock among males.

The phase IV clinical study analyzes what interactions people have when they take Pioglitazone and Lenalidomide. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.

What is Pioglitazone?

Pioglitazone has active ingredients of pioglitazone hydrochloride. It is often used in diabetes. eHealthMe is studying from 12,864 Pioglitazone users. Check the latest studies of Pioglitazone.

What is Lenalidomide?

Lenalidomide has active ingredients of lenalidomide. eHealthMe is studying from 52,881 Lenalidomide users. Check the latest studies of Lenalidomide.

On Aug, 11, 2026

54 people who take Pioglitazone and Lenalidomide together, and have interactions are studied.

Pioglitazone and Lenalidomide drug interactions.

What are the common drug interactions of Pioglitazone and Lenalidomide, by gender? *:

female:

Anaemia (lack of blood)
Hypotension (abnormally low blood pressure)
Platelet count decreased
Pneumonia
Syncope (loss of consciousness with an inability to maintain postural tone)
Thrombosis (formation of a blood clot inside a blood vessel)
Parainfluenzae virus infection
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Diarrhoea
Muscle spasms (muscle contraction)

male:

Septic shock (shock due to blood infection)
Hepatic enzyme increased
Blood calcium decreased
Blood creatinine increased
Dyspepsia (indigestion)
Erythema (redness of the skin)
Fatigue (feeling of tiredness)
Full blood count decreased
Haemoglobin decreased
Headache (pain in head)

What are the common drug interactions of Pioglitazone and Lenalidomide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Erythema (redness of the skin)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypotension (abnormally low blood pressure)
Joint warmth
Pneumonia
Pulmonary embolism (blockage of the main artery of the lung)
Rash pruritic (redness with itching)
Renal failure (kidney dysfunction)
Urinary tract infection

60+:

Hypotension (abnormally low blood pressure)
Anaemia (lack of blood)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Diarrhoea
Eosinophilia (eosinophil count in the peripheral blood exceeds)
Fatigue (feeling of tiredness)
Renal failure (kidney dysfunction)
Renal failure acute (rapid kidney dysfunction)
White blood cell count decreased
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 29 people, 53.70%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 11 people, 20.37%
Mucosal Inflammation (infection of mucous membrane): 11 people, 20.37%
Insomnia (sleeplessness): 11 people, 20.37%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 11 people, 20.37%
Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 4 people, 7.41%
Type 2 Diabetes: 3 people, 5.56%
Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 3 people, 5.56%
Cough: 3 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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