Pioglitazone and Proventil drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Pioglitazone (pioglitazone hydrochloride) and Proventil (albuterol). Common drug interactions include headache among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Pioglitazone and Proventil. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.
What is Pioglitazone?
Pioglitazone has active ingredients of pioglitazone hydrochloride. It is often used in diabetes. eHealthMe is studying from 12,864 Pioglitazone users. Check the latest studies of Pioglitazone.
What is Proventil?
Proventil has active ingredients of albuterol. It is often used in asthma. eHealthMe is studying from 16,110 Proventil users. Check the latest studies of Proventil.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
31 people who take Pioglitazone and Proventil together, and have interactions are studied.

What are the common drug interactions of Pioglitazone and Proventil, by gender? *:
female:
- Headache (pain in head)
- Asthenia (weakness)
- Chronic kidney disease
- Nasopharyngitis (inflammation of the nasopharynx)
- Renal failure (kidney dysfunction)
- Arthralgia (joint pain)
- Bone disorder
- Dermatitis allergic (inflammation of the skin due allergic reaction)
- Drug ineffective
- Fatigue (feeling of tiredness)
male:
- Chronic kidney disease
- Pain
- Dizziness
- Emotional distress
- Flatulence (flatus expelled through the anus)
- Gait disturbance
- Pain in extremity
- Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
- Renal failure (kidney dysfunction)
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
What are the common drug interactions of Pioglitazone and Proventil, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Bone density decreased
- Chronic kidney disease
- Emotional distress
- Pain
- Renal failure (kidney dysfunction)
- Tooth loss
30-39:
n/a
40-49:
- Cough
- Dyspnoea (difficult or laboured respiration)
- Hallucination (an experience involving the perception of something not present)
50-59:
- Chronic kidney disease
- Mouth haemorrhage (bleeding from mouth)
- Renal failure (kidney dysfunction)
- Tongue injury
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Nephropathy (damage to or disease of a kidney)
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Urinary tract infection
- Confusional state
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
60+:
- Headache (pain in head)
- Nasopharyngitis (inflammation of the nasopharynx)
- Myalgia (muscle pain)
- Pain
- Pruritus (severe itching of the skin)
- Pyrexia (fever)
- Rash
- Swelling
- Tooth fracture
- Urticaria (rash of round, red welts on the skin that itch intensely)
What are the existing conditions these people have? *
- High Blood Cholesterol: 11 people, 35.48%
- High Blood Pressure: 7 people, 22.58%
- Pain: 7 people, 22.58%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 19.35%
- Urticaria (rash of round, red welts on the skin that itch intensely): 6 people, 19.35%
- Multiple Allergies (allergy to multiple agents): 4 people, 12.90%
- Type 2 Diabetes: 4 people, 12.90%
- Fluid Retention (an abnormal accumulation of fluid in the blood): 4 people, 12.90%
- Infection: 4 people, 12.90%
- Idiopathic Urticaria (allergic reactions, presence of hives with unknown cause): 4 people, 12.90%
* Approximation only. Some reports may have incomplete information.
Do you take Pioglitazone and Proventil?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Pioglitazone (12,864 reports)
- Proventil (16,110 reports)
Browse all drug interactions of Pioglitazone and Proventil:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Pioglitazone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Proventil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pioglitazone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Proventil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on pioglitazone hydrochloride and albuterol (the active ingredients of Pioglitazone and Proventil, respectively), and Pioglitazone and Proventil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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