Piperacillin and Olanzapine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Piperacillin (piperacillin sodium) and Olanzapine (olanzapine). Common drug interactions include syncope among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Piperacillin and Olanzapine. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Piperacillin?

Piperacillin has active ingredients of piperacillin sodium. eHealthMe is studying from 5,597 Piperacillin users. Check the latest studies of Piperacillin.

What is Olanzapine?

Olanzapine has active ingredients of olanzapine. It is often used in bipolar disorder. eHealthMe is studying from 69,242 Olanzapine users. Check the latest studies of Olanzapine.

On Jul, 26, 2026

46 people who take Piperacillin and Olanzapine together, and have interactions are studied.

Piperacillin and Olanzapine drug interactions.

What are the common drug interactions of Piperacillin and Olanzapine, by gender? *:

female:

Syncope (loss of consciousness with an inability to maintain postural tone)
Ejection fraction decreased (systolic heart failure)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood albumin decreased
Blood alkaline phosphatase increased
Blood calcium decreased
Blood glucose increased
Blood lactate dehydrogenase increased
Blood phosphorus decreased

male:

Pyrexia (fever)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Lung disorder (lung disease)
Lymphadenopathy (disease or enlargement of lymph nodes)
Nausea (feeling of having an urge to vomit)
Pericardial effusion (fluid around the heart)
Pleural effusion (water on the lungs)
Polyserositis (general inflammation of serous membranes, with effusion)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Syncope (loss of consciousness with an inability to maintain postural tone)

What are the common drug interactions of Piperacillin and Olanzapine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Febrile neutropenia (fever with reduced white blood cells)
Neuropathy peripheral (surface nerve damage)
Stomatitis (inflammation of mucous membrane of mouth)
Vocal cord paralysis

10-19:

Febrile neutropenia (fever with reduced white blood cells)
Infection
Syncope (loss of consciousness with an inability to maintain postural tone)
Bacteraemia (presence of bacteria in the blood)
Myositis (inflammation of the muscles)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Phlebitis (inflammation of the walls of a vein)
Sepsis (a severe blood infection that can lead to organ failure and death)
Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot)

20-29:

Abdominal pain
Appendicitis (inflammation of the appendix)
Ascites (accumulation of fluid in the abdominal cavity)
Cardiomegaly (increased size of heart than normal)
Diarrhoea
Nausea (feeling of having an urge to vomit)
Pericardial effusion (fluid around the heart)
Pleural effusion (water on the lungs)
Polyserositis (general inflammation of serous membranes, with effusion)
Pyrexia (fever)

30-39:

Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Alanine aminotransferase increased
Blood alkaline phosphatase increased
Cross sensitivity reaction
Drug hypersensitivity
Gamma-glutamyltransferase increased
Hepatocellular injury (liver injury)
Leukocytosis (increased white blood cells)
Lymphadenopathy (disease or enlargement of lymph nodes)
Pyrexia (fever)

40-49:

n/a

50-59:

Syncope (loss of consciousness with an inability to maintain postural tone)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Delirium (wild excitement)
Cross sensitivity reaction
Drug hypersensitivity
Drug level increased
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)

60+:

Ejection fraction decreased (systolic heart failure)
Alanine aminotransferase increased
Blood urea decreased
Blood uric acid decreased
C-reactive protein increased
Carbon dioxide decreased
Colitis (inflammation of colon)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Diarrhoea
Encephalopathy (functioning of the brain is affected by some agent or condition)

What are the existing conditions these people have? *

Psychotic Disorder: 12 people, 26.09%
Constipation: 11 people, 23.91%
Headache (pain in head): 10 people, 21.74%
Brain Abscess: 10 people, 21.74%
Nausea (feeling of having an urge to vomit): 10 people, 21.74%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 21.74%
Stress And Anxiety: 10 people, 21.74%
Pain: 9 people, 19.57%
Febrile Neutropenia (fever with reduced white blood cells): 8 people, 17.39%
Hypersensitivity: 6 people, 13.04%

* Approximation only. Some reports may have incomplete information.

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