Piperacillin and Restoril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Piperacillin (piperacillin sodium) and Restoril (temazepam). Common drug interactions include chronic kidney disease among females and cellulitis among males.

The phase IV clinical study analyzes what interactions people have when they take Piperacillin and Restoril. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Piperacillin?

Piperacillin has active ingredients of piperacillin sodium. eHealthMe is studying from 5,597 Piperacillin users. Check the latest studies of Piperacillin.

What is Restoril?

Restoril has active ingredients of temazepam. It is often used in insomnia. eHealthMe is studying from 13,522 Restoril users. Check the latest studies of Restoril.

On Jul, 18, 2026

13 people who take Piperacillin and Restoril together, and have interactions are studied.

Piperacillin and Restoril drug interactions.

What are the common drug interactions of Piperacillin and Restoril, by gender? *:

female:

Chronic kidney disease
Renal failure (kidney dysfunction)
Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
Renal tubular necrosis (death of kidney tubules)

male:

Cellulitis (infection under the skin)
Sepsis (a severe blood infection that can lead to organ failure and death)
Rectal abscess (pus in rectum)
Renal failure (kidney dysfunction)
Dyspnoea (difficult or laboured respiration)
Hypotension (abnormally low blood pressure)
Renal failure acute (rapid kidney dysfunction)
Scrotal abscess (pus in scrotum)
Scrotal erythema (redness of scrotum area)
Thrombocytopenia (decrease of platelets in blood)

What are the common drug interactions of Piperacillin and Restoril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Sepsis (a severe blood infection that can lead to organ failure and death)
Abscess (pus)
Anal abscess
Cellulitis (infection under the skin)
Chronic kidney disease
Groin abscess (pus in groin)
Leukocytosis (increased white blood cells)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Perineal abscess
Perirectal abscess

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac disorder
Cellulitis (infection under the skin)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Erythema (redness of the skin)
Lung infection
Pyrexia (fever)
Renal tubular necrosis (death of kidney tubules)

What are the existing conditions these people have? *

Weight Decreased: 4 people, 30.77%
Hypotension (abnormally low blood pressure): 4 people, 30.77%
Type 2 Diabetes: 4 people, 30.77%
Pain: 4 people, 30.77%
Nausea (feeling of having an urge to vomit): 3 people, 23.08%
Stress And Anxiety: 3 people, 23.08%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 15.38%
Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 2 people, 15.38%
Sinus Congestion (blockage of sinus): 2 people, 15.38%
Neutropenic Colitis (inflammation of the cecum, often with involvement of the ascending colon and ileum, a life threatening condition): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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