Piperacillin and Senna drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Piperacillin (piperacillin sodium) and Senna (senna). Common drug interactions include haemoglobin decreased among females and sepsis among males.

The phase IV clinical study analyzes what interactions people have when they take Piperacillin and Senna. It is created by eHealthMe based on reports of 72 people who take the same drugs from the FDA, and is updated regularly.

What is Piperacillin?

Piperacillin has active ingredients of piperacillin sodium. eHealthMe is studying from 5,597 Piperacillin users. Check the latest studies of Piperacillin.

What is Senna?

Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.

On Jul, 19, 2026

72 people who take Piperacillin and Senna together, and have interactions are studied.

Piperacillin and Senna drug interactions.

What are the common drug interactions of Piperacillin and Senna, by gender? *:

female:

Haemoglobin decreased
Interstitial lung disease
Mucosal inflammation (infection of mucous membrane)
Platelet count decreased
Sepsis (a severe blood infection that can lead to organ failure and death)
Haemorrhagic transformation stroke (haemorrhages develop inside areas of ischemia)
Malaise (a feeling of general discomfort or uneasiness)
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Pulmonary embolism (blockage of the main artery of the lung)
Abdominal pain

male:

Sepsis (a severe blood infection that can lead to organ failure and death)
Thrombocytopenia (decrease of platelets in blood)
Anion gap increased
Anxiety
Asthenia (weakness)
Back disorder
Body temperature increased
Chills (felling of cold)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Emotional distress

What are the common drug interactions of Piperacillin and Senna, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Nausea (feeling of having an urge to vomit)
Vomiting
Lower respiratory tract infection
Pneumonia
Diarrhoea
Excessive eye blinking (excessive blinking is dry eyes)
Pain in jaw
Disease progression
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Chest pain

40-49:

Ileus (a painful obstruction of the ileum or other part of the intestine)
Malignant neoplasm progression (cancer tumour came back)
Pleural effusion (water on the lungs)
Abscess limb (limb infection)
Cellulitis (infection under the skin)
Dyspnoea (difficult or laboured respiration)
Groin abscess (pus in groin)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Perineal abscess
Sepsis (a severe blood infection that can lead to organ failure and death)

50-59:

Cardiac failure congestive
Chills (felling of cold)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Oedema peripheral (superficial swelling)
Septic shock (shock due to blood infection)
Staphylococcal bacteraemia (a bacterial infection of blood)
Staphylococcal infection (an infection with staphylococcus bacteria)
Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot)
Pneumonia
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

60+:

Dyskinesia (abnormality or impairment of voluntary movement)
Presyncope
Bone marrow failure
Duodenitis (inflammation of the duodenum)
Melaena (the passage of black, tarry stools)
Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Pancreatitis acute (sudden inflammation of pancreas)
Asthenia (weakness)
Hyperhidrosis (abnormally increased sweating)
Sepsis (a severe blood infection that can lead to organ failure and death)

What are the existing conditions these people have? *

Breast Cancer Metastatic: 23 people, 31.94%
Nausea And Vomiting: 13 people, 18.06%
Nausea (feeling of having an urge to vomit): 11 people, 15.28%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 11 people, 15.28%
Back Pain: 9 people, 12.50%
High Blood Pressure: 8 people, 11.11%
Diarrhea: 8 people, 11.11%
Pneumonia: 7 people, 9.72%
Fever: 7 people, 9.72%
Chills (felling of cold): 7 people, 9.72%

* Approximation only. Some reports may have incomplete information.

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