Piqray and Hydroxyzine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Piqray (alpelisib) and Hydroxyzine (hydroxyzine hydrochloride). Common drug interactions include blood glucose increased among females.
The phase IV clinical study analyzes what interactions people have when they take Piqray and Hydroxyzine. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Piqray?
Piqray has active ingredients of alpelisib. eHealthMe is studying from 7,290 Piqray users. Check the latest studies of Piqray.
What is Hydroxyzine?
Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,070 Hydroxyzine users. Check the latest studies of Hydroxyzine.
16 people who take Piqray and Hydroxyzine together, and have interactions are studied.

What are the common drug interactions of Piqray and Hydroxyzine, by gender? *:
female:
- Blood glucose increased
- Diarrhoea
- Oral pain
- Anaphylactic reaction (serious allergic reaction)
- Breast cancer
- Cough
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Dyspnoea (difficult or laboured respiration)
- Erythema (redness of the skin)
- Hyperglycaemia (high blood sugar)
male:
n/a
What are the common drug interactions of Piqray and Hydroxyzine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Disease progression
- Metastases to central nervous system (cancer spreads to central nervous system)
50-59:
- Dyspnoea (difficult or laboured respiration)
- Erythema (redness of the skin)
- Hypersensitivity
- Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
- Malaise (a feeling of general discomfort or uneasiness)
- Pneumonitis (inflammation of the walls of the alveoli in the lungs)
- Rash
- Rash erythematous (redness of the skin)
- Urinary tract infection
- Anaphylactic reaction (serious allergic reaction)
60+:
- Disease progression
- Interstitial lung disease
- Pneumonia
- Death
- Breast cancer
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Hyperglycaemia (high blood sugar)
- Pyrexia (fever)
What are the existing conditions these people have? *
- Breast Cancer: 6 people, 37.50%
- Breast Cancer Metastatic: 4 people, 25.00%
- Rashes (redness): 2 people, 12.50%
- Diabetes: 2 people, 12.50%
- Procedural Pain: 2 people, 12.50%
- Breast Cancer Female: 2 people, 12.50%
- Pain: 2 people, 12.50%
- Oral Candidiasis (fungal infection of mouth): 2 people, 12.50%
- Nausea (feeling of having an urge to vomit): 2 people, 12.50%
- Muscle Spasms (muscle contraction): 2 people, 12.50%
* Approximation only. Some reports may have incomplete information.
Do you take Piqray and Hydroxyzine?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Piqray (7,290 reports)
- Hydroxyzine (54,070 reports)
Browse all drug interactions of Piqray and Hydroxyzine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Piqray:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Hydroxyzine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Piqray and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Hydroxyzine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
- Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on alpelisib and hydroxyzine hydrochloride (the active ingredients of Piqray and Hydroxyzine, respectively), and Piqray and Hydroxyzine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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