Plaquenil and Diprivan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Plaquenil (hydroxychloroquine sulfate) and Diprivan (propofol). Common drug interactions include hyperglycaemia among females and jugular vein thrombosis among males.

The phase IV clinical study analyzes what interactions people have when they take Plaquenil and Diprivan. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Plaquenil?

Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in systemic lupus erythematosus. eHealthMe is studying from 91,018 Plaquenil users. Check the latest studies of Plaquenil.

What is Diprivan?

Diprivan has active ingredients of propofol. eHealthMe is studying from 6,496 Diprivan users. Check the latest studies of Diprivan.

On Jul, 13, 2026

45 people who take Plaquenil and Diprivan together, and have interactions are studied.

Plaquenil and Diprivan drug interactions.

What are the common drug interactions of Plaquenil and Diprivan, by gender? *:

female:

Hyperglycaemia (high blood sugar)
Foot deformity (functional disability of foot)
Otitis externa (external ear infection)
Nausea (feeling of having an urge to vomit)
Anxiety
Cor pulmonale chronic (long lasting enlargement of the right ventricle of the heart)
Gastroduodenitis (an inflammation of the mucous membrane of the stomach and duodenum)
Uterine enlargement
Weight decreased
Pyrexia (fever)

male:

Jugular vein thrombosis (clot in jugular vein)
Pneumonia bacterial (pneumonia associated with bacterial infection)
Blood alkaline phosphatase increased
Blood calcium decreased
Blood creatinine increased
Blood glucose increased
Blood sodium increased
Glomerular filtration rate decreased
Proteinuria (presence of protein in the urine)
Renal disorder (kidney disease)

What are the common drug interactions of Plaquenil and Diprivan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Septic shock (shock due to blood infection)
Abdominal pain
Confusional state
Nausea (feeling of having an urge to vomit)
Right ventricular failure (right half of the heart fails to work)
Skin wound
Somnolence (a state of near-sleep, a strong desire for sleep)
Vomiting
Acute respiratory distress syndrome

40-49:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Exposed bone in jaw
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Hypokalaemia (low potassium)
Stress cardiomyopathy (stress-induced chronic disease of the heart muscle)

50-59:

Appendicitis (inflammation of the appendix)
Nausea (feeling of having an urge to vomit)
Cardiac failure congestive
Aptyalism (deficiency or absence of saliva)
Asthma
Bone disorder
Bone erosion
Bone fragmentation
Bone pain
Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)

60+:

Jugular vein thrombosis (clot in jugular vein)
Liver disorder (liver diseases)
Pneumonia bacterial (pneumonia associated with bacterial infection)
Staphylococcal bacteraemia (a bacterial infection of blood)
Staphylococcal infection (an infection with staphylococcus bacteria)
Thrombosis (formation of a blood clot inside a blood vessel)
Fall
Hepatitis cholestatic (flow of bile from the liver is slowed or blocked)
Renal disorder (kidney disease)
Subdural haematoma (blood collects between the skull and the surface of the brain)

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 30 people, 66.67%
Thrombocytopenia (decrease of platelets in blood): 11 people, 24.44%
Pain: 3 people, 6.67%
Anaesthesia: 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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