Plaquenil and Lecithin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Plaquenil (hydroxychloroquine sulfate) and Lecithin (phosphatidylcholine). Common drug interactions include fatigue among females and device failure among males.

The phase IV clinical study analyzes what interactions people have when they take Plaquenil and Lecithin. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Plaquenil?

Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in systemic lupus erythematosus. eHealthMe is studying from 91,018 Plaquenil users. Check the latest studies of Plaquenil.

What is Lecithin?

Lecithin has active ingredients of phosphatidylcholine. It is often used in high blood cholesterol. eHealthMe is studying from 2,310 Lecithin users. Check the latest studies of Lecithin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 14, 2026

24 people who take Plaquenil and Lecithin together, and have interactions are studied.

Plaquenil and Lecithin drug interactions.

What are the common drug interactions of Plaquenil and Lecithin, by gender? *:

female:

Fatigue (feeling of tiredness)
Infusion site pain
Arthralgia (joint pain)
Infusion site erythema (reddening of the skin at infusion site)
Pain in jaw
Infusion site haemorrhage (bleeding from infusion site)
Infusion site pruritus (severe itching at infusion site)
Neck pain
Diarrhoea
Fall

male:

Device failure
Device dislocation
Infusion site erythema (reddening of the skin at infusion site)
Infusion site haemorrhage (bleeding from infusion site)

What are the common drug interactions of Plaquenil and Lecithin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Headache (pain in head)
Pain in jaw
Decreased appetite
Dizziness
Dyspnoea (difficult or laboured respiration)
Infusion site erythema (reddening of the skin at infusion site)
Infusion site irritation
Infusion site pain
Migraine (headache)
Muscle spasms (muscle contraction)

40-49:

Muscular weakness (muscle weakness)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Pathological fracture (broken bone caused by disease)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Pharyngitis (inflammation of the pharynx, causing a sore throat)
Platelet count increased
Postoperative wound complication
Pulmonary granuloma (tiny lump of inflamed tissue in the lungs)
Pyrexia (fever)

50-59:

Pain
Pain in extremity
Hypophagia (reduced food intake)
Inflammation
Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Neck pain
Pulmonary hypertension (increase in blood pressure in the lung artery)
Abdominal distension
Abdominal hernia

60+:

n/a

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 12 people, 50.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 25.00%
Depression: 4 people, 16.67%
Muscle Spasms (muscle contraction): 3 people, 12.50%
Insomnia (sleeplessness): 3 people, 12.50%
Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 12.50%
Drowsiness: 2 people, 8.33%
Constipation: 2 people, 8.33%
Chest Pain: 2 people, 8.33%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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