Plaquenil and Olmetec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Plaquenil (hydroxychloroquine sulfate) and Olmetec (olmesartan medoxomil). Common drug interactions include chest pain among females and acidosis among males.

The phase IV clinical study analyzes what interactions people have when they take Plaquenil and Olmetec. It is created by eHealthMe based on reports of 65 people who take the same drugs from the FDA, and is updated regularly.

What is Plaquenil?

Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in systemic lupus erythematosus. eHealthMe is studying from 91,018 Plaquenil users. Check the latest studies of Plaquenil.

What is Olmetec?

Olmetec has active ingredients of olmesartan medoxomil. It is often used in high blood pressure. eHealthMe is studying from 7,904 Olmetec users. Check the latest studies of Olmetec.

On Jul, 10, 2026

65 people who take Plaquenil and Olmetec together, and have interactions are studied.

Plaquenil and Olmetec drug interactions.

What are the common drug interactions of Plaquenil and Olmetec, by gender? *:

female:

Chest pain
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hepatic enzyme increased
Hyperlipidaemia (presence of excess lipids in the blood)
Joint swelling
Knee arthroplasty
Multiple-drug resistance
Oedema peripheral (superficial swelling)
Peripheral swelling
Varicose vein (veins that have become enlarged and tortuous)

male:

Acidosis (build-up of carbon dioxide in the blood)
Blood creatinine increased
Tension headache
Upper respiratory tract infection
Urticaria (rash of round, red welts on the skin that itch intensely)
Hyperkalaemia (damage to or disease of the kidney)
Acute respiratory distress syndrome
Herpes zoster
Liver disorder (liver diseases)
Malaise (a feeling of general discomfort or uneasiness)

What are the common drug interactions of Plaquenil and Olmetec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Pyrexia (fever)
Diarrhoea
Upper respiratory tract infection
Acidosis (build-up of carbon dioxide in the blood)
Blood creatinine increased
Cellulitis (infection under the skin)
Chest pain
Contusion (a type of hematoma of tissue in which capillaries)
Erythema multiforme (a type of hypersensitivity reaction)
Pharyngitis (inflammation of the pharynx, causing a sore throat)

40-49:

Fatigue (feeling of tiredness)
Fluid retention (an abnormal accumulation of fluid in the blood)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Oropharyngeal plaque (hard deposit on oropharynx)
Peripheral swelling
Pneumonia
Somnolence (a state of near-sleep, a strong desire for sleep)
Vomiting
Hypoaesthesia (reduced sense of touch or sensation)

50-59:

Hand fracture

60+:

Arthralgia (joint pain)
Pain
Chest discomfort
Cough
Infusion related reaction
Mouth ulceration (mouth ulcers)
Oedema (fluid collection in tissue)
Oxygen saturation decreased
Rash erythematous (redness of the skin)
Blood pressure decreased

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 45 people, 69.23%
Lupus Nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 8 people, 12.31%
Fever: 8 people, 12.31%
Diarrhea: 8 people, 12.31%
Cellulitis (infection under the skin): 8 people, 12.31%
Pharyngitis (inflammation of the pharynx, causing a sore throat): 6 people, 9.23%
Erythema Multiforme (a type of hypersensitivity reaction): 6 people, 9.23%
Chest Pain: 6 people, 9.23%
High Blood Cholesterol: 5 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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