Plaquenil and Timolol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Plaquenil (hydroxychloroquine sulfate) and Timolol (timolol). Common drug interactions include weight decreased among females and bundle branch block left among males.

The phase IV clinical study analyzes what interactions people have when they take Plaquenil and Timolol. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Plaquenil?

Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in systemic lupus erythematosus. eHealthMe is studying from 91,018 Plaquenil users. Check the latest studies of Plaquenil.

What is Timolol?

Timolol has active ingredients of timolol. It is often used in glaucoma. eHealthMe is studying from 9,142 Timolol users. Check the latest studies of Timolol.



On Jul, 15, 2026

24 people who take Plaquenil and Timolol together, and have interactions are studied.

Plaquenil and Timolol drug interactions.

What are the common drug interactions of Plaquenil and Timolol, by gender? *:

female:

  1. Weight decreased
  2. Dizziness
  3. Nausea (feeling of having an urge to vomit)
  4. Arthralgia (joint pain)
  5. Vomiting
  6. Fall
  7. Feeding disorder (when children refuse to eat certain food groups)
  8. Vertigo
  9. Contusion (a type of hematoma of tissue in which capillaries)
  10. Seizure (abnormal excessive or synchronous neuronal activity in the brain)

male:

  1. Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
  2. Cardiac arrest
  3. Cataract (clouding of the lens inside the eye)
  4. Cerebrospinal fluid leakage
  5. Dental caries
  6. Eye haemorrhage (bleeding in the eye)
  7. Faecaloma (hard mass of fecal matter)
  8. Gait disturbance
  9. Groin pain
  10. Headache (pain in head)

What are the common drug interactions of Plaquenil and Timolol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Blood creatinine increased
  2. Drug eruption (adverse drug reaction of the skin)

60+:

  1. Arthralgia (joint pain)
  2. Dizziness
  3. Dehydration (dryness resulting from the removal of water)
  4. Fall
  5. Gait disturbance
  6. Headache (pain in head)
  7. Hypertension (high blood pressure)
  8. Insomnia (sleeplessness)
  9. Poor venous access
  10. Sinusitis (inflammation of sinus)

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 11 people, 45.83%
  2. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 16.67%
  3. High Blood Pressure: 4 people, 16.67%
  4. Uveitis (inflammation of the uvea): 3 people, 12.50%
  5. Macular Degeneration (painless eye condition that leads to the gradual loss of central vision): 3 people, 12.50%
  6. Iridocyclitis (inflammation of the iris and ciliary body of the eye): 3 people, 12.50%
  7. Urinary Tract Infection: 2 people, 8.33%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Plaquenil and Timolol?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Plaquenil and Timolol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Plaquenil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Timolol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Plaquenil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Timolol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on hydroxychloroquine sulfate and timolol (the active ingredients of Plaquenil and Timolol, respectively), and Plaquenil and Timolol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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