Plaquenil and Zoledronic drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Plaquenil (hydroxychloroquine sulfate) and Zoledronic (zoledronic acid). Common drug interactions include nausea among females.

The phase IV clinical study analyzes what interactions people have when they take Plaquenil and Zoledronic. It is created by eHealthMe based on reports of 70 people who take the same drugs from the FDA, and is updated regularly.

What is Plaquenil?

Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in systemic lupus erythematosus. eHealthMe is studying from 91,018 Plaquenil users. Check the latest studies of Plaquenil.

What is Zoledronic?

Zoledronic has active ingredients of zoledronic acid. eHealthMe is studying from 29,812 Zoledronic users. Check the latest studies of Zoledronic.

On Jul, 11, 2026

70 people who take Plaquenil and Zoledronic together, and have interactions are studied.

Plaquenil and Zoledronic drug interactions.

What are the common drug interactions of Plaquenil and Zoledronic, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Diarrhoea
Arthralgia (joint pain)
Blood magnesium increased
Blood potassium increased
Cyst (a closed sac)
Deafness neurosensory
Dry eye (lack of adequate tears)
Epigastric discomfort
Joint swelling

male:

n/a

What are the common drug interactions of Plaquenil and Zoledronic, by age (0-1 to 60+)? *:

0-1:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Blood pressure decreased
Dizziness
Haemoglobin increased
Headache (pain in head)
Red blood cell count increased

40-49:

Crepitations (noises are produced by the rubbing of parts one against the other)
Heart rate increased
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Nodule (a growth of abnormal tissue)
Polychondritis (progressive inflammation of cartilage and other connective tissue)
Vasculitis (inflammation of a blood vessel or blood vessels)
Vertigo
Weight decreased
Diarrhoea
Fatigue (feeling of tiredness)

50-59:

Antinuclear antibody positive
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Arthropathy
Asthma
Back pain
Blood glucose increased
Blood immunoglobulin g decreased
Blood immunoglobulin m decreased
Blood urea increased
Body tinea (ringworm of the body)

60+:

Nausea (feeling of having an urge to vomit)
Diarrhoea
Cyst (a closed sac)
Deafness neurosensory
Dry eye (lack of adequate tears)
Epigastric discomfort
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteopenia (a condition where bone mineral density is lower than normal)
Pleural fibrosis (formation of fibrous tissue in lung)
Presbyacusis (age-related hearing loss)

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 41 people, 58.57%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 29 people, 41.43%
Pain: 20 people, 28.57%
Dry Eyes (lack of adequate tears): 18 people, 25.71%
Adenomatous Polyposis Coli ((fap) is an inherited condition in which numerous polyps form mainly in the epithelium of the large intestine): 18 people, 25.71%
Sleep Disorder: 11 people, 15.71%
Osteoporosis (bones weak and more likely to break): 9 people, 12.86%

* Approximation only. Some reports may have incomplete information.

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