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Plavix and Ocaliva drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Plavix (clopidogrel bisulfate) and Ocaliva (obeticholic acid). Common drug interactions include sinusitis among females and decreased appetite among males.

The phase IV clinical study analyzes what interactions people have when they take Plavix and Ocaliva. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Plavix?

Plavix has active ingredients of clopidogrel bisulfate. It is often used in stent. eHealthMe is studying from 151,178 Plavix users. Check the latest studies of Plavix.

What is Ocaliva?

Ocaliva has active ingredients of obeticholic acid. eHealthMe is studying from 6,919 Ocaliva users. Check the latest studies of Ocaliva.

On Jul, 18, 2026

45 people who take Plavix and Ocaliva together, and have interactions are studied.

Plavix and Ocaliva drug interactions.

What are the common drug interactions of Plavix and Ocaliva, by gender? *:

female:

  1. Sinusitis (inflammation of sinus)
  2. Back pain
  3. Balance disorder
  4. Constipation
  5. Depression
  6. Discomfort
  7. Peripheral swelling
  8. Pneumonia
  9. Throat irritation
  10. Tongue coated

male:

  1. Decreased appetite
  2. Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
  3. Pruritus (severe itching of the skin)
  4. Discomfort
  5. Fatigue (feeling of tiredness)
  6. Ocular icterus (presence of jaundice seen in the sclera of the eye)
  7. Oral pain

What are the common drug interactions of Plavix and Ocaliva, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
  2. Pruritus (severe itching of the skin)
  3. Ocular icterus (presence of jaundice seen in the sclera of the eye)

50-59:

  1. Pruritus (severe itching of the skin)
  2. Gastric disorder (disease of stomach)
  3. Nephrolithiasis (calculi in the kidneys)
  4. Ovarian cyst (fluid filled sac of the ovary)
  5. Rash
  6. Rash papular (redness with papule)

60+:

  1. Pruritus (severe itching of the skin)
  2. Discomfort
  3. Sinusitis (inflammation of sinus)
  4. Throat irritation
  5. Tongue coated
  6. Tremor (trembling or shaking movements in one or more parts of your body)
  7. Acarodermatitis (skin inflammation caused by mites (acarids))
  8. Liver disorder (liver diseases)
  9. Purpura (purplish discoloration of the skin)
  10. Decreased appetite

What are the existing conditions these people have? *

  1. Biliary Cirrhosis Primary (primary biliary cirrhosis (pbc) is a long-term liver disease that damages the small bile ducts in the liver. the build-up of bile damages the liver): 5 people, 11.11%
  2. Pain: 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Plavix and Ocaliva?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Plavix and Ocaliva:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Plavix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ocaliva:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Plavix and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ocaliva and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on clopidogrel bisulfate and obeticholic acid (the active ingredients of Plavix and Ocaliva, respectively), and Plavix and Ocaliva (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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