Plavix and Propacet 100 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Plavix (clopidogrel bisulfate) and Propacet 100 (acetaminophen; propoxyphene napsylate). Common drug interactions include cardiac failure congestive among females and adrenal mass among males.

The phase IV clinical study analyzes what interactions people have when they take Plavix and Propacet 100. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Plavix?

Plavix has active ingredients of clopidogrel bisulfate. It is often used in stent. eHealthMe is studying from 151,178 Plavix users. Check the latest studies of Plavix.

What is Propacet 100?

Propacet 100 has active ingredients of acetaminophen; propoxyphene napsylate. eHealthMe is studying from 1,282 Propacet 100 users. Check the latest studies of Propacet 100.



On Jul, 13, 2026

23 people who take Plavix and Propacet 100 together, and have interactions are studied.

Plavix and Propacet 100 drug interactions.

What are the common drug interactions of Plavix and Propacet 100, by gender? *:

female:

  1. Cardiac failure congestive
  2. Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
  3. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  4. Dyskinesia (abnormality or impairment of voluntary movement)
  5. Ear congestion
  6. Ear discomfort
  7. Hypoaesthesia (reduced sense of touch or sensation)
  8. Migraine (headache)
  9. Muscle tightness
  10. Excoriation (to tear or wear off the skin of)

male:

  1. Adrenal mass
  2. Breast mass
  3. Pain in extremity
  4. Pneumonia
  5. Pulmonary congestion (congestion in the lungs)
  6. Breast tenderness
  7. Chest pain
  8. Constipation
  9. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  10. Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)

What are the common drug interactions of Plavix and Propacet 100, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Asthma
  2. Back disorder
  3. Blood pressure increased
  4. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  5. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  6. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  7. Diplopia (double vision)
  8. Dizziness
  9. Drug ineffective
  10. Dyspnoea (difficult or laboured respiration)

60+:

  1. Dysphagia (a condition in which swallowing is difficult or painful)
  2. Tardive dyskinesia (a disorder that involves involuntary movements)
  3. Sensation of foreign body
  4. Tinnitus (a ringing in the ears)
  5. Balance disorder
  6. Blindness
  7. Dizziness
  8. Neck pain
  9. Nervous system disorder (a general class of medical conditions affecting the nervous system)
  10. Postnasal drip

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 14 people, 60.87%
  2. Neck Pain: 3 people, 13.04%

* Approximation only. Some reports may have incomplete information.

Do you take Plavix and Propacet 100?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Plavix and Propacet 100:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Plavix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Propacet 100:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Plavix and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Propacet 100 and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on clopidogrel bisulfate and acetaminophen; propoxyphene napsylate (the active ingredients of Plavix and Propacet 100, respectively), and Plavix and Propacet 100 (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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