Plegridy and Flomax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Plegridy (peginterferon beta-1a) and Flomax (tamsulosin hydrochloride). Common drug interactions include influenza like illness among females and hyperhidrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Plegridy and Flomax. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Plegridy?

Plegridy has active ingredients of peginterferon beta-1a. eHealthMe is studying from 14,764 Plegridy users. Check the latest studies of Plegridy.

What is Flomax?

Flomax has active ingredients of tamsulosin hydrochloride. It is often used in enlarged prostate. eHealthMe is studying from 52,865 Flomax users. Check the latest studies of Flomax.



On Jul, 19, 2026

19 people who take Plegridy and Flomax together, and have interactions are studied.

Plegridy and Flomax drug interactions.

What are the common drug interactions of Plegridy and Flomax, by gender? *:

female:

  1. Influenza like illness
  2. Injection site erythema (redness at injection site)
  3. Fatigue (feeling of tiredness)
  4. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  5. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  6. Hypoaesthesia (reduced sense of touch or sensation)
  7. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  8. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  9. Injection site pruritus (severe itching at injection site)
  10. Adverse event

male:

  1. Hyperhidrosis (abnormally increased sweating)
  2. Muscle fatigue (a condition in which muscles cannot exert their normal force)
  3. Gait disturbance
  4. General symptom
  5. Mobility decreased (ability to move is reduced)
  6. Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
  7. Bladder disorder
  8. Dysstasia (difficulty in standing)
  9. Fall
  10. Pyrexia (fever)

What are the common drug interactions of Plegridy and Flomax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Hypoaesthesia (reduced sense of touch or sensation)
  2. Influenza like illness
  3. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  4. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

30-39:

  1. Influenza like illness
  2. Injection site erythema (redness at injection site)
  3. Injection site pruritus (severe itching at injection site)

40-49:

  1. Asthenia (weakness)
  2. Bladder disorder
  3. Dysstasia (difficulty in standing)
  4. Fall
  5. Pyrexia (fever)
  6. Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
  7. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  8. Thrombosis (formation of a blood clot inside a blood vessel)

50-59:

  1. Pneumonia
  2. Urinary tract infection

60+:

  1. Hyperhidrosis (abnormally increased sweating)
  2. Muscle fatigue (a condition in which muscles cannot exert their normal force)
  3. Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
  4. Pain
  5. Asthenia (weakness)
  6. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
  7. Constipation
  8. Gastric ulcer perforation (stomach hole due to ulcer)
  9. Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)
  10. Incontinence (lack of moderation or self-control)

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 17 people, 89.47%
  2. Gait Disturbance: 4 people, 21.05%
  3. Movement Disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness): 2 people, 10.53%
  4. Weakness: 1 person, 5.26%
  5. Urine Flow Decreased: 1 person, 5.26%
  6. Urinary Incontinence (inability to control the flow of urine and involuntary urination): 1 person, 5.26%
  7. Swelling: 1 person, 5.26%
  8. Sinus Disorder (disease of sinus): 1 person, 5.26%
  9. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 1 person, 5.26%
  10. Insomnia (sleeplessness): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Plegridy and Flomax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Plegridy:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Flomax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Plegridy and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Flomax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on peginterferon beta-1a and tamsulosin hydrochloride (the active ingredients of Plegridy and Flomax, respectively), and Plegridy and Flomax (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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